Re: Hardy-Weinberg law

From: Perplexed in Peoria (jimmenegay_at_sbcglobal.net)
Date: 06/24/04 

Date: Thu, 24 Jun 2004 04:29:24 +0000 (UTC)

"Anon." <bob.ohara@SOD.OFF.Spammers.helsinki.fi> wrote in message
news:cbc9qn$27b0$1@darwin.ediacara.org...
> Perplexed in Peoria wrote:
> >>In essence, any finite population will become inbred over time (at least
> >>to some extent), and this increases homozygosity.
> >
> >
> > Boy, are you going to feel foolish after you get a good night's sleep
> > and review what you have written :-)
> >
> I'm not sure I feel foolish, but I agree it would be better to have
> written this:
>
> In essence, any finite population will become inbred over time (at least
> to some extent), and this means an increase in homozygosity.

I must apologize for being unclear in indicating what was foolish.
There is nothing foolish about the quoted statement taken in
isolation (and I admit that I apparently isolated it).

What was foolish was to make this statement in the context of
a discussion of the Hardy-Weinberg law, and in particular the
"infinite population assumption" in derivations of the law.
My point here is well made by Hoelzer and Hunt. You are
either succumb to or ignoring an ambiguity in the word
"homozygosity" in this context. Do you mean to suggest
that the kind of inbreeding that increases in a finite
population over time has anything to do with invalidating
P^2: 2PQ : Q^2 ??

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