Re: Hardy-Weinberg lawt

From: John Edser (edser_at_tpg.com.au)
Date: 07/01/04 

Date: Thu, 1 Jul 2004 15:46:30 +0000 (UTC)

"Anon." <bob.ohara@SOD.OFF.Spammers.helsinki.fi>wrote

> > JM:-
> > Bob, you might check your texts. According to what I read, you have
> > just described a binomial distribution (with n=2). The corresponding
> > trinomial distribution would have six cells:
> > ( p^2, q^2, r^2, 2pq, 2pr, 2qr) with the constraint that p+q+r=1.

> BOH:-
> No, a binomial distribution has N events, with two possible outcomes per
> event (often called "success" and "failure", or if p=0.5, H and T). For
> H-W, we have three outcomes: two homozygotes and a heterozygote, and N
> is the size of the sample taken from the population.
> The number of copies on one of the alleles in an individual is
> binomially distributed, but H-W is a statement of the proportions of the
> three genotypes in the population (this is not to say that the "alleles
> per individual" interpretation is incorrect, but just that it isn't used).

JE:-
Yes: "The number of copies on one of the
alleles in an individual is binomially distributed".
Yes: "this is not to say that the "alleles
per individual" interpretation is incorrect,
but just that it isn't used".

What Dr O'Hara is admitting is that we
exit biological reality where all genes
only exist as fitness dependent within
fertile individuals and enter a Mad
Hatter world where all genes are fitness
free.

Regards,

John Edser
Independent Researcher

PO Box 266
Church Pt
NSW 2105
Australia

edser@tpg.com.au

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