Re: DNA before RNA in OOL?
- From: "Perplexed in Peoria" <jimmenegay@xxxxxxxxxxxxx>
- Date: Tue, 5 Apr 2005 01:14:40 -0400 (EDT)
"tinyurl.com/uh3t" <rem642b@xxxxxxxxx> wrote in message news:d2ngu2$2nof$1@xxxxxxxxxxxxxxxxxxxxxx
> > From: "Perplexed in Peoria" <jimmenegay@xxxxxxxxxxxxx>
> > Isn't it possible that DNA was the first genetic polymer?
>
> Possible, but not likely. Did you see the speculation I posted a few
> months ago about how the early replicators might have later
> polymerized? Given these early replicators were just whatever happened
> to be catalytic loops with fecundity greater than one, its highly
> unlikely they were either DNA or RNA.
No, I didn't see that (or don't remember it if I did see it. In order to
have a genetic polymer, ISTM that you need four things.
1. A source of energy to drive the polymerization.
2. Heritable variation in genotype. (i.e. a heteropolymer with some kind
of template replication).
3. Heritable variation in phenotype. (i.e. the polymer does something that
influences fitness).
4. An organism to which the "gene" applies.
Did your proposal address all four of these issues?
Other people might dispute whether item #4 belongs in the list. But it
seems to me that a naked, selfish gene is better considered an organism
in itself, rather than a gene. But that is semantics, and not worth
arguing about.
.
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