Recombination hot-spots or are they not spots?



Greetings,

The notion of recombination hot-spots has been around a while, but this
recent Science article comparing the spatial distribution of hot-spots
between human and chimp genomes has me wondering. Are recombination
hot-spots really discretely different in terms of recombination rate from
the rest of the genome, or is there a continuum of recombination rates? I
am interested in examining the frequency distribution of mutation rates
across the genome, so I would appreciate any pointers to the literature if
this has already been done.

Regards,

Guy Hoelzer


.



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