Re: Fundamental theorems, dilemmas, fitness, and information.




"John Edser" <edser@xxxxxxxxxx> wrote in message news:d9g3uq$d76$1@xxxxxxxxxxxxxxxxxxxxxx
> "Perplexed in Peoria" jimmenegay@xxxxxxxxxxxxx wrote:-
> > JM:-
> > It is important to realize that Fisher's limit and
> > Haldane's limit are independent. For example, consider
> > the rate at which a genetically determined 10 point
> > increase in the "IQ" of a population can take place.
> > The question is whether the increase in "IQ" happens
> > faster if it is caused by a single beneficial allele,
> > of if it is caused by 10 alleles at 10 loci each of
> > which bestows a 1 point increase in "IQ".
>
> JE:-
> Of course the latter event "10 alleles at 10 loci each of which bestows
> a 1 point increase in "IQ"" does not empirically exist for gene fitness
> as in:
> 10 alleles at 10 loci each of which bestows a 1 point increase in
> fitness so just the one IQ trait has an additive fitness of 10. Fisher
> assumed that unless a trait was additive it was not heritable.

Not quite correct, John. Fisher says that there is an additive
part and a non-additive part to the effect of any allele on fitness.
Only the additive portion of the effect is heritable. At least that
is how I understand it.


.



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