Re: Haldane's Dilemma - clarifications - and Felsenstein
- From: "Perplexed in Peoria" <jimmenegay@xxxxxxxxxxxxx>
- Date: Sat, 17 Jun 2006 13:26:58 -0400 (EDT)
"Walter ReMine" <science@xxxxxxxx> wrote in message news:e6v5gh$682$1@xxxxxxxxxxxxxxxxxxxxxx
My paper, Cost Theory and the Cost of Substitution -- a clarification"
is published, and available for free here:
http://SaintPaulScience.com/CostTheory1.pdf
The paper clarifies many long-standing confusions about the cost of
substitution, which is the fundamental concept behind Haldane's
Dilemma. The paper was peer-reviewed by evolutionary geneticists,
including James Crow and Warren Ewens, who acknowledge it is correct.
Thx Walter. I finally get to read your paper.
The paper is relatively easy to read for a pop-gen paper. Though I
am an amateur, I find no reason to disagree with Crow and Ewens that
it is correct. And it does clarify some things - most notably the
(to my mind bizarre) notion that neutral substitutions also incur a
'cost' but are not 'cost limited'. And additional, even eccentric,
viewpoints on an issue are always inherently clarifying.
However, I remain unconvinced by the main argument in the paper - that
this viewpoint is the best one, and perhaps the only one that does not
generate confusion. I see no particular reason why the paper should
not have been published, but I don't think that the serious pop-gen
community has been cheated of the opportunity to think about these
problems in the "right" way by the failure to publish.
Warning: people who are intrigued or outraged by Walter's argument
the Haldane's Dilemma presents a serious challenge to evolutionary
theory in the context of the speed of hominid evolution will be
disappointed by this paper. The paper merely provides some definitional
and mathematical background to THAT argument. The argument itself
must be found elsewhere.
.
- References:
- Haldane's Dilemma - clarifications - and Felsenstein
- From: Walter ReMine
- Haldane's Dilemma - clarifications - and Felsenstein
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