Haldane's Dilemma and quantitative genetics

For several months, I have been wasting part of my time trying to
understand "cost of substitution" from the viewpoint of population
genetics and/or information theory. But recently, I was struck by the
idea of treating the count of advantageous alleles in an individual
as a quantitative trait, and looking at the rate of change in this
trait using Price's equation and/or the 'Breeder's Equation'.

I'm even more of a novice in quantitative genetics and analysis of
variance than I am in pop-gen, but so far it seems to me that this
approach to the issue is illuminating.

Question for ReMine, Felsenstein, or anyone else familiar with what
ReMine calls "the cost literature": Has anyone published anything
along these lines?


.

Relevant Pages

  • Re: Reproductive Excess: Is Required
    ... >> So ReMine has agreed with me, ... >abundantly clear that his cost concept is IRRELEVANT to Haldane's ... >substitutions require no reproductive excess. ... >is the moment a cost of substitution is incurred. ...
    (sci.bio.evolution)
  • Re: Haldanes Dilemma - again, again, again, ...
    ... I'm aware of that paper - which ReMine calls a clarification. ... substitution as substitution of genes at the same locus. ... Leonard Nunney has written a paper "The cost of natural selection ... but here we might run into the max capacity of the environment (as ...
    (sci.bio.evolution)
  • Re: Haldanes Dilemma - again, again, again, ...
    ... Natural Selection" to be more able to write something relevant. ... My problem now is that ReMine is rewriting the whole thing apparently ... It argues that the "cost of natural selection" ... My reading of Haldane's paper shows that it is discussing substitutions ...
    (sci.bio.evolution)
  • Re: Felsenstein and reproductive excess
    ... > That scenario would REQUIRE a reproduction rate of AT LEAST ... ReMine is correctly proposing that a finite reproductive limit must ... at no time does ReMine compare this cost ... Neo Darwinists do not discriminate between fertile parents ...
    (sci.bio.evolution)
  • Re: The cost of substitution
    ... Remine is endlessly repeating his statement that the cost of natural selection ... >substitution CLEAR in the evolutionary literature? ... Ewens and Crow are contradicting ...
    (sci.bio.evolution)