Re: Do unneeded antibiotic treatments help evolve resistant bacteria?



That's another interesting point. Genetic exchanges do occur
between bacteria, even those of radically different type. I don't
know what the likelihood is antibiotic resistance might be
transferred in this way, but it does seem worth investigating.
Genetic exchanges between bacteria were first discovered because
of antibiotic resistance. I don't have the reference, but antibiotic
resistance was discovered in a case were it accidently was transferred
from one species to another. This occurred sometime in the late 50s,
when they didn't really know much about DNA. I don't know if this type
of experiment is still legal, but for a while antibiotic resistance
was one of the major means of studying genetic transfer. Now, they
have other means of monitoring the transfer of genes (histoimmune
typing, DNA, etc.)
The main means of exchanging genetic material is conjugation,
where plasmids are exchanged. I am very much interested in what types
of hybridization barrier are involved in this transfer. I am sure it
is not unlimited. Your doctors may be thinking that bacteria can only
conjugate with closely related species.
Does anyone know whether true meiosis is more or less selective
than bacterial conjugation? This could be an important question with
regards to public health policy.


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