Paper: The evolution of genetic networks by non-adaptive processes
- From: "Robert Karl Stonjek" <rstonjek@xxxxxxxxxxxxxx>
- Date: Wed, 19 Sep 2007 18:31:09 -0400 (EDT)
Nature Reviews Genetics 8, 803-813 (October 2007) | doi:10.1038/nrg2192
The evolution of genetic networks by non-adaptive processes
Michael Lynch
Abstract
Although numerous investigators assume that the global features of genetic
networks are moulded by natural selection, there has been no formal
demonstration of the adaptive origin of any genetic network. This Analysis
shows that many of the qualitative features of known transcriptional
networks can arise readily through the non-adaptive processes of genetic
drift, mutation and recombination, raising questions about whether natural
selection is necessary or even sufficient for the origin of many aspects of
gene-network topologies. The widespread reliance on computational procedures
that are devoid of population-genetic details to generate hypotheses for the
evolution of network configurations seems to be unjustified.
Source: Nature Genetics
http://www.nature.com/nrg/journal/v8/n10/abs/nrg2192.html
Posted by
Robert Karl Stonjek
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