Metal-in-protein mechanism discovered (was: News: Scientists unwrap the elements of life)

From: "Robert Karl Stonjek" <rston...@xxxxxxxxxxxxxx>
In a paper published today in Nature, the team led by Professor
Nigel Robinson have revealed a mechanism that ensures the right
metal goes to the right protein. ... to ensure a copper and a
manganese protein wrap around the correct metal atoms they do
this in different parts of the cell, in zones which contain
different metals. Therefore, which protein attaches to which
metal is determined by where the folding action takes place in
the cell. ... Once folded, the manganese site is buried, the
metal trapped inside the protein, and so the manganese protein
can subsequently co-exist with the copper protein because its
metal becomes impervious to replacement by metals further up the
Irving-Williams series.

If true, this is a profound discovery. Thanks for posting!!

.

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