Re: Ammonium Salicylate

From: Dirk Bruere at Neopax (dirk_at_neopax.com)
Date: 11/10/04 

Date: Wed, 10 Nov 2004 19:26:52 +0000

hanson wrote:

> "Dirk Bruere at Neopax" <dirk@neopax.com> wrote in message
> news:2uqs2kF2e3ph5U1@uni-berlin.de...
> Can anyone tell me anything useful about Ammonium Salicylate?
> AmSal Properties?
> Can't find MSDS on the Net.
> Has it medicinal uses?
> Seen it as an ingredient on a bottle of suntan lotion,
>
> [Don Haarmann]
> [AmSal] it is not harmful/hazardous to two legged carbon units
> there will be no MSDS. --- Merck's Index says:-
> A.- Antriheum.; Antipyr.; Germic; Expector. -
> Uses : In febrile conditions, bronchitis, artic. rhumat., &c. -
> Dose 2-20 grains (0.2-1.3 Gm.) in wafers.
>
> [Dirk]
>
>>I was wondering whether it [AmSal] might be formed on/in
>>the skin when (say Cu Salicylate is applied topically. And
>>whether there may be benefits from using it on its own.
>>Dirk
>>
>
> [hanson]
> It is highly unlikely but not impossible that
> CuSal + SkinProteinNH2 ---> NH4Sal
> Not impossible, because Merck Index 13 says that AmSal is an
> analgesic and is used as "topically to loosen psoriatic scales".
> This is right up the alley of your research application.
> So, give AmSal a try without the Cu in it. Now, you have also
> reported some success with Cu-chelates/CuSal. Therefore try
> also Cu(NH3)2-Sal or Cu(NH3)4-Sal and similar combos.
> The more Ammonia the higher the alkalinity, so caution.
> Their solubility you must find by experiment.
> Be aware that, as was posted, the light sensitivity of AmSal
> may cause a stability problem. Naturally, the Cu is the mix
> will enhance this, in addition with the Cu's propensity to form
> radicals. Radicals are a two etched sword. They may multiply
> the clinical properties you look for but side effects may outweigh
> the gain. Check it out.
> hanson

Thanks.
Will do. 

-- 
Dirk
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