Coupling HPLC with a magnetic susceptibility detector?
- From: "Farooq W" <farooq.w@xxxxxxxxx>
- Date: 29 Apr 2005 07:46:11 -0700
During a casual discussion a colleague came up with the possibility of
coupling HPLC with a magnetic susceptibility detector say a electronic
Gouy balance after suitable modification for producing a real time
plot, for detecting paramagnetic transition metal compounds say in a
new synthetic inorganic work or for quantitation purposes. The solution
would constantly pass through a U-shaped capillary placed in that
detector, and the chromatogram would consist of magnetic susceptibility
versus time or volume. Thus one would selectively detect paramagnetic
specie in presence of others.
The basic idea is somewhat similiar to thermogravitmetry curve where
change in mass is continuously monitored against temperature.
Is the above idea feasible and useful at all, note this is just an
idea, I am not sure if magnetic susceptibility can be measured in
solution. I am asking this because some of you might have had good
experience with those things. If this is a good idea, this would
constitue a research project for me. Somewhere I read that HPLC was
coupled with NMR but they were not sucessful because the response time
was too slow.
.
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