integration

The best way to evaluate the indefinite integral
∫ (3x^2 + 1)(5x^3 + 5x −12)^5 dx is
a. By expanding and applying the power rule
b. By substitution 5x3 + 5x − 12 = u
c. By substitution 3x 2 + 1 = u
I need little more explanation
.