Re: Statin - CoQ10 suppression (Arch Neurol, 6/04)

From: listener (listener_at_nospam.net)
Date: 09/21/04 

Date: 21 Sep 2004 15:58:50 GMT

John Merlano <someone@home.somewhere> wrote in
news:cxzmx31k31l6.zdz691du4415.dlg@40tude.net:

> On Sun, 19 Sep 2004 04:58:44 GMT, Sharon Hope wrote:
>
> Doesn't supplementing with CoQ10 help solve the problem of statins
> preventing the body from making it? Something like 100 mg of CoQ10 in
> softgel form?

From:
http://faculty.washington.edu/ely/coenzq10.html

"HMG-CoA reductase inhibitors used to treat elevated blood cholesterol
levels by blocking cholesterol biosynthesis also block CoQ10 biosynthesis
(13). The resulting lowering of blood CoQ10 level is due to the partially
shared biosynthetic pathway of CoQ10 and cholesterol. In patients with
heart failure this is more than a laboratory observation. It has a
significant harmful effect which can be negated by oral CoQ10
supplementation(14)."

L.