Re: Side effects: drugs called statins

From: Ed (Ed_at_houseofbuttcrack.com)
Date: 12/04/04 

Date: Sat, 04 Dec 2004 14:47:36 -0500

I take 40 mg of pravachol daily and have had no side effects.

On 4 Dec 2004 10:31:01 -0800, "zwalanga@yahoo.com"
<zwalanga@yahoo.com> wrote:

>Side effects: drugs called statisn. Following this story, and along
>with it in the online and print versions, are lists of the side effects
>of statins.
>
>Drugs called statins can lower cholesterol levels, a risk factor for
>heart disease. But they can also cause serious problems.
>Rita Daly and Karen Palmer Report
>
>STAFF REPORTERS
>
>Every day, more than 3 million Canadians pop a cholesterol pill,
>comforted by the thought it could one day save their lives.
>
>Dozens of studies have shown these pills, called statins, lower the
>body's "bad" cholesterol, a risk factor for heart disease. The drugs
>work safely and effectively for millions who suffer with cardiovascular
>disease.
>
>But a growing number of researchers, doctors and patients are becoming
>concerned that statins - the world's fastest-growing class of drugs
>- are being too readily prescribed to people who don't need them and
>are causing more serious side effects than previously thought.
>
>The debate has sparked a scientific tug-of-war among medical
>researchers, drug makers and regulators, and underlines crucial
>questions about how a drug's benefits are weighed against its risks and
>who decides whether it should be on the market.
>
>The answers aren't easy. There is no magic number of injuries or
>deaths, no standard formula anywhere in the world that determines if a
>drug may be unsafe.
>
>One of the more common and known side effects of statins is muscle
>pain, but the drugs can also cause muscle damage or myopathy, which can
>also be a sign of a rare, potentially fatal muscle-wasting disease
>called rhabdomyolysis. It's one of the most serious side effects, along
>with liver and kidney damage, particularly at higher doses or when
>taken with certain other medications.
>
>Lorraine Smith, 65, of Whitby, was prescribed the statin Zocor strictly
>to control her cholesterol. She was on lower doses for seven years when
>her cholesterol rose again, and her doctor doubled the dose.
>
>Shortly after, she awoke one morning paralyzed with pain. First her
>arm, then her back, her legs, her hands, her fingers - every muscle,
>every joint felt so stiff she couldn't move.
>
>"It just seemed overnight, I had pain in my whole body ... it got worse
>and worse," Smith says.
>
>Seven different doctors sent her for a battery of tests, scopes and
>scans to determine why this once-avid bowler and walker could no longer
>shop for more than 10 minutes before the debilitating aches would set
>in.
>
>They found nothing. But Smith, who two years later still lives with the
>pain, suspects the cholesterol drug was to blame.
>
>Online message boards give her little hope, since they're filled with
>hundreds of others who claim to have suffered the same kind of muscle
>problems.
>
>"I was shocked to find so many people who were having the exact same
>problems."
>
>
>Statins, such as Lipitor, Zocor and Crestor, are hailed as the wonder
>drugs of the 21st century, the "new Aspirin" that lowers cholesterol,
>staves off heart attacks and reduces the risk of heart disease, North
>America's number one killer.
>
>There are six on the market in Canada, and they're wildly popular.
>Doctors wrote more than 15 million prescriptions for statins last year.
>More than 8 million were prescribed for Pfizer Inc.'s Lipitor, making
>it the nation's - and the world's - top-selling drug. Globally,
>statin sales last year reached an unprecedented $26 billion (U.S.)
>
>They're also part of a rapidly growing phenomenon in prescription
>medicine - pharmaceuticals geared more to prevention than cure, that
>offer a pill to fix years of stress, unhealthy habits or the effects of
>aging. In the case of statins, people are expected to be on them for
>life, and require regular checkups and blood tests.
>
>Heart experts say millions worldwide benefit from the drugs.
>
>"These are very, very efficacious drugs," says Dr. George Fodor, a
>cardiologist and head of research at the University of Ottawa's
>Prevention and Rehabilitation Centre who has conducted
>industry-sponsored statin studies for more than 15 years. He says
>cholesterol drugs have proven over and over to be safe.
>
>"In the United Kingdom, a very conservative country, the statin (Zocor)
>was released over the counter (this summer) because it was found safer
>than Aspirin. It's an exceedingly safe drug."
>
>Yet critics warn the drugs' side effects are being underplayed in a
>marketing push to treat millions more people.
>
>Maple Leafs hockey coach Pat Quinn praised his own cholesterol
>medication at a media brunch this summer at Toronto's Hockey Hall of
>Fame. Pharmaceutical giant Pfizer paid for the event.
>
>Perched on a stool under television camera lights and surrounded by a
>phalanx of reporters, Quinn spoke of his own heart scare two years ago
>and the need for 8 million Canadians to get tested for high
>cholesterol. He later acknowledged he got a "modest" fee for his
>appearance.
>
>"There's a $26 billion-a-year industry that ensures you hear all about
>the beneficial side (of the drugs)," says Dr. Beatrice Golomb, a
>neurologist at the University of California-San Diego, who is
>researching the full spectrum of statin side effects.
>
>"There really isn't any group that makes sure people hear about the
>other side."
>
>The drug industry, among the most profitable in the world, constantly
>battles an image that Big Pharma is bad. It fights back by arguing it
>invests heavily in medical research, is highly regulated and promotes
>only products that have already been rigorously tested and approved.
>
>"In the pharmaceutical industry, it somehow becomes very nasty and
>suspect because we're marketing drugs," says Sheila Murphy, a
>spokesperson for Merck and Co., which makes the statins Zocor and
>Mevacor.
>
>Company executives also say they work closely with government
>regulators to monitor drug safety, reporting all serious side effects
>they come across within 15 days.
>
>Health Canada, the country's regulator, relies on those reports and
>voluntary ones filed by health-care professionals - doctors,
>pharmacists, hospital workers to search for clues that a drug might be
>unsafe. The voluntary system has its flaws. It's estimated fewer than
>one in 10 adverse reactions are ever reported, but they are still used
>as a surveillance tool.
>
>An analysis of the Canadian adverse drug reaction data, obtained by the
>Toronto Star, shows there were 1,739 reports filed where a statin was
>suspected in a reaction, from 1988 when the first one hit the market to
>the end of 2003.
>
>Of those, 1,024 were deemed serious.
>
>In August, 2001, Bayer's Baycol was pulled from the market because of
>dozens of cases worldwide involving rhabdomyolysis, the muscle-wasting
>disease. Canadian data show 76 cases of the disease involving Baycol
>had been reported by the end of 2003, 31 of which were filed after it
>was withdrawn and lawsuits launched.
>
>Health Canada says statin-related rhabdomyolysis cases are "very rare,"
>occurring in less than one in 10,000 patients. This month, a U.S. Food
>and Drug Administration study found Baycol triggered the potentially
>fatal muscle disease 10 times more often than Lipitor, Zocor and
>Pravachol, although Bayer disputes the findings.
>
>The latest figures from Health Canada for statins on the market show
>that up to the end of October, there were 62 reports of rhabdomyolysis
>in patients taking Lipitor, 18 for Zocor, 12 for Merck's Mevacor, five
>for Pravachol, made by Bristol-Myers Squibb, and 11 for AstraZeneca's
>Crestor.
>
>As of the end of 2003, according to the Star's analysis, there were 44
>deaths reported where a statin was suspected - five of which,
>involving Baycol, were filed after the drug was pulled. Health Canada
>and drug makers say that without further study, it is difficult to know
>whether the drug alone or in combination with another medication, or an
>underlying medical condition, caused the reactions.
>
>Peter Kung, 43, of Scarborough, will probably never know what caused
>the pain and weakness in his right shoulder and arm. A diabetic, he was
>already taking medication to help control his blood sugar levels, as
>well as blood pressure pills, when prescribed Lipitor. At 5-foot-9 and
>205 pounds, he had unsuccessfully tried diet to control his high
>cholesterol.
>
>It wasn't until he saw a Lipitor commercial that cited muscle pain as a
>common side effect that he decided the risk of muscle damage wasn't
>worth the benefits of the drug.
>
>One doctor diagnosed it as frozen shoulder, a common complication of
>diabetes, but Kung still wonders if it was the drug.
>
>Golomb, whose research on statins is almost complete, says even a blood
>test designed to detect statin-related muscle damage isn't catching all
>cases. New evidence shows doctors may be overlooking cases like
>Lorraine Smith's, whose test was normal, Golomb says.
>
>Her statin research also involves a $4.5 million study, funded by the
>U.S. National Institutes of Health, of patients who have experienced
>blackouts and memory loss while on the drug. Such side effects aren't
>surprising considering the brain is rich in cholesterol, she says.
>
>Makers of statins have not acknowledged cognitive problems as a side
>effect.
>
>Dr. Jack Watters, a senior medical director for Pfizer, says a body of
>academic opinion states "if you treat with statins, you will improve
>cognitive health and prevent the onset of dementia and Alzheimer's."
>
>
>--------------------------------------------------------------------------------
>`It just seemed overnight, I had pain in my whole body ... it got worse
>and worse'
>
>Lorraine Smith, Zocor user
>
>--------------------------------------------------------------------------------
>
>
>
>At the core of the statin debate is this question: Is cholesterol a
>useful marker for heart disease and, if so, does everyone with high
>cholesterol need drugs?
>
>A soft, fat-like substance in blood and cells vital to various
>functions, including transporting vitamins to tissue, cholesterol was
>first identified as a risk factor in a Massachusetts study in 1950. It
>was listed among 240 risk factors, including male baldness, short
>stature and creased ear lobes.
>
>Ever since, science has seesawed on just how prominent a role
>cholesterol plays and whether it is really a predictor of a fatal heart
>attack.
>
>Some heart experts say study data overwhelmingly show cholesterol is a
>major risk factor. Other experts have looked at the same data and
>concluded high cholesterol doesn't necessarily put you at risk. They
>say researchers with financial ties to statin makers are pushing drugs
>harder as a convenient alternative to lifestyle changes.
>
>Dr. James Wright, director of the B.C.-government funded Therapeutics
>Initiative that evaluates drugs on the market, says independent
>analyses of statin studies show middle-aged men with coronary heart
>disease have, at best, a 2 per cent better chance of living longer
>while on the drugs.
>
>No survival benefit has been proven for women, men over 70, or men at a
>lower cardiac risk, he says.
>
>High cholesterol poses a problem if someone in the family had a heart
>attack or stroke at a young age - just as smoking, high blood
>pressure and lack of exercise are major risk factors for heart disease.
>On the other hand, he says, if you have high cholesterol in your family
>and there have been no heart attacks, it indicates your cholesterol is
>of no consequence.
>
>"Yet, now we've got people and their parents, none of whom have had a
>coronary event, all on drugs. It's a crazy concept."
>
>When Lorraine Smith was prescribed Zocor nine years ago, she didn't
>have cardiovascular disease, and there was no family history of heart
>problems. She did have high cholesterol, mild angina and was a light
>smoker.
>
>At first, a 20-milligram dose lowered her cholesterol. Then, it started
>to rise again, and Smith's doctor upped her dose, first to 40
>milligrams, then, two years ago, to the highest dose possible, 80
>milligrams. Within weeks, she became crippled with pain. Smith says she
>was aware the drugs could cause mild muscle pain but learned only later
>that severe muscle damage is a known side effect of statins, especially
>at high doses.
>
>Her family doctor immediately cut the dosage in half, then told her to
>stop the drug altogether. No link has been made to the drug, yet the
>pain continues, and since going off the drug her cholesterol levels
>have risen only slightly.
>
>In August, Merck, Zocor's maker, released a study showing the 80
>milligram dose increased the risk of muscle problems and was no more
>effective than lower doses.
>
>Company officials contend the drug is safe when used appropriately.
>
>Most clinical trials of statins have primarily studied middle-aged men,
>but statin makers - constantly exploring the wider potential for the
>drugs - say all indications in those studies show women and elderly
>people stand to benefit.
>
>"I contest the fact there is reduced benefit in elderly people," says
>Pfizer's Watters.
>
>"The fact that they may not necessarily have been studied doesn't
>necessarily show that you can conclude, therefore, that there was no
>effect. That is an entirely spurious argument."
>
>Dr. Ruth McPherson, a endocrinologist at the University of Ottawa Heart
>Institute, says it would be unethical not to treat women and the
>elderly.
>
>"There's nothing different about arteriosclerosis in women versus men
>and the elderly versus the young, and if we deny appropriate treatment
>to women, just saying we're not going to do this until we have a study
>with 10,000 women, it doesn't make any sense."
>
>More than 30 American and British researchers and doctors from medical
>schools such as Harvard, Stanford and Johns Hopkins have recently lined
>up against this argument, however.
>
>This fall, in a petition to the National Institutes Of Health, they
>called for an independent review of U.S. cholesterol guidelines -
>revised in 2001 and again this summer - charging millions more will
>now be prescribed a drug they may not need and can cause side effects.
>Adding force to their demand and spawning accusations of bias was the
>revelation that eight of the nine guideline authors had financial ties
>to makers of statins, receiving consulting and lecture fees, and
>research money.
>
>Canadian cholesterol guidelines, published in the Canadian Medical
>Association Journal, have also been revised twice in the past four
>years, resulting in more people being prescribed statins.
>
>The four authors of those guidelines have also received money from
>statin manufacturers. Three have sat on drug company advisory boards
>and three have received research grants to conduct statin studies and
>travel expenses to speak at scientific meetings sponsored by
>pharmaceutical companies.
>
>The authors, interviewed by the Star, acknowledge while there is a
>perception of bias, the guidelines are based on sound scientific
>evidence.
>
>"I have family members who are very much upset about the relationship
>of drug companies to academia in general, and guideline makers in
>particular," says author Dr. Jiri Frolich, a cardiologist at St. Paul's
>Hospital at the University of British Columbia.
>
>But "if you really want to be good in your field, I would say it is
>almost impossible or extremely difficult not to be touched by industry
>in one way or another."
>
>
>Part of the frenzy surrounding cholesterol has been created by drug
>makers battling over the blockbuster statin market.
>
>There are six statins on the market, made by different companies -
>and they're at war.
>
>Since the first of these drugs, Merck's Mevacor, hit the market in the
>late 1980s, manufacturers have raced to prove one statin is more
>effective and safer than the next.
>
>Dozens of clinical trials have been published to show one drug lowered
>cholesterol better, another reduced chances of a second heart attack,
>while yet another prevented a heart attack from happening at all.
>
>At the same time, statin makers have run costly advertising and
>education campaigns, partnering with health organizations to teach the
>public about the dangers of cholesterol and flooding doctors' offices
>with promotional literature.
>
>Pfizer, which launched Lipitor onto the market in the U.S. in 1996 and
>Canada in 1997, has been particularly ambitious, partnering with the
>Canadian Diabetes Association as well as entertainment and sports
>celebrities, like Pat Quinn.
>
>The meteoric rise of statins has suffered its setbacks.
>
>Bayer has been accused of knowing Baycol's risk long before it warned
>the public. Bayer denies the accusation, saying the drug carried
>warnings about rhabdomyolysis when it was approved.
>
>It is also the target of numerous lawsuits in which Bayer has agreed to
>pay more than $1 billion (U.S.) out of court. A settlement was reached
>in March in a Canadian class action commenced by Toronto law firm
>Rochon Genova, with no admission of liability on Bayer's part.
>
>Responding to the Star's questions about reported cases linked to
>Baycol in Canada, Bayer said in a statement: "It is likely that many of
>these events relate to medical conditions that have never been shown to
>be associated with statin use."
>
>Kim Coleman, whose 59-year-old mother, Pearl Inwood, died while on
>Baycol, says she wonders why the drug wasn't pulled sooner if they knew
>it was causing problems.
>
>"We were never aware of this muscle problem," says Coleman, whose
>mother died in July, 2001, of complications from severe rhabdomyolysis
>at a Kingston hospital and who is part of the class action. "It was the
>shock of our lives. One week she was in hospital, the next week she was
>gone."
>
>The drug was pulled two weeks after her mother's death.
>
>Crestor, the newest statin to hit the market, has also run into
>problems. Health Canada has issued two warnings on the drug since it
>came on the market in February, 2003. Last week, the regulator said
>there have been 11 reports of rhabdomyolysis in patients using Crestor.
>
>Public Citizen, a 160,000-member consumer advocacy group in the U.S.,
>has called for a ban on the drug. And two weeks ago, a senior FDA
>researcher named Crestor among five medications that he said needs
>closer scrutiny.
>
>Carley Vint-Reed, scientific director of cardiovascular research for
>AstraZeneca, says all data available show Crestor to be a safe
>molecule.
>
>"It's very clear that all of the statins on the market are safe,
>including Crestor. That safety profile has remained in the same
>relative risk since the beginning of the first statin."
>
>
>STATIN-RELATED REACTIONS*
>Types of reactions to statins, a class of cholesterol-lowering drugs,
>as reported to Health Canada and entered into its Canadian Adverse Drug
>Reaction Information System, from the date the drug was approved to the
>end of 2003. The reports, filed mainly by health care providers,
>reflect a suspicion or opinion that the drug may have been involved in
>an adverse reaction, and, alone, cannot be used to establish a cause
>and effect relationship. There are other important caveats associated
>with this data that should be read. Drugs are listed by active
>ingredient, followed by the total number of prescriptions filled in
>Canada from 1999 to 2003. In brackets is the brand name the drug was
>first marketed as.**
>
>You can look up the specifics of a reaction term using MedlinePlus'
>Medical Dictionary
>
>*Data Source: Health Canada. Analysis: Toronto Star
>**Source: IMS Health - Canada
>
>ATORVASTATIN, 27.5 million - (LIPITOR) (monograph)
>
>RHABDOMYOLYSIS 43SGOT INCREASED 42CREATINE KINASE INCREASED 41SGPT
>INCREASED 41MUSCLE PAIN 33MYOCARDIAL INFARCTION 23WEAKNESS GENERALIZED
>23NAUSEA 22ABDOMINAL PAIN 20MYALGIA 20HEPATIC ENZYMES INCREASED
>19MUSCLE WEAKNESS 19RASH 18ALKALINE PHOSPHATASE SERUM INCR 17CREATINE
>PHOSPHOKINASE INCREASED 16FATIGUE 16CHEST PAIN 15CONDITION AGGRAVATED
>15FEVER 15HEADACHE 15HYPERTENSION 15DIARRHOEA 14ITCHING 14PAIN
>14BRONCHITIS 13BREATH SHORTNESS 12CEREBROVASCULAR DISORDER 12CORONARY
>ARTERY DISORDER 12COUGHING 12LDH INCREASED 12LEG PAIN 12MYOSITIS
>12PANCREATITIS 12STROKE 12CPK INCREASED 11CREATININE BLOOD INCREASED
>11RENAL FAILURE ACUTE 11VOMITING 11BILIRUBIN INCREASED 10CONVULSIONS
>10INSOMNIA 10MUSCLE ACHE 10PRURITUS 10WEIGHT DECREASE 10BLOOD PRESSURE
>INCREASED 9FALL 9GAMMA-GT INCREASED 9INFECTION 9JAUNDICE 9LIVER
>FUNCTION TESTS ABNORMAL NOS 9PROSTATIC DISORDER 9VISION DECREASED
>9WALKING DIFFICULTY 9BACK PAIN 8DIZZINESS 8GAMMA-GLUTAMYLTRANSFERASE
>INCR. 8HAEMOGLOBIN DECREASED 8HEART ATTACK 8URINARY TRACT INFECTION
>8ARTHRITIS 7CHOLELITHIASIS 7CONSTIPATION 7ERYTHEMA 7HERNIA NOS
>7HYPOTENSION 7JOINT PAIN 7MALAISE 7SINUSITIS 7ANGINA PECTORIS 6ANXIETY
>6APPETITE DECREASED 6BLOOD SUGAR INCREASED 6BREATHING DIFFICULT
>6BURNING SENSATION 6CHRONIC OBSTRUCT AIRWAYS DISEASE 6CRAMPS LEGS
>6DIABETES MELLITUS 6DYSPEPSIA 6DYSPNOEA 6FEELING UNWELL 6FIBRILLATION
>ATRIAL 6GASTRITIS 6HEPATITIS 6HYPERGLYCAEMIA 6HYPERTRIGLYCERIDAEMIA
>6MUSCLE CRAMP 6MYOGLOBINURIA 6OEDEMA LEGS 6PALPITATION 6PNEUMONIA
>6RENAL FAILURE NOS 6TINGLING SKIN 6WEIGHT INCREASE 6ADENOCARCINOMA NOS
>5ALLERGIC REACTION 5ANGINA PECTORIS AGGRAVATED 5ANGIOEDEMA 5ANOREXIA
>5ASTHENIA 5CATARACT 5CELLULITIS 5DERMATITIS 5GASTROESOPHAGEAL REFLUX
>5INFECTION VIRAL 5LEUCOPENIA 5MYOPATHY 5NEOPLASM NOS 5PAIN
>NECK/SHOULDER 5PULMONARY CARCINOMA 5THROMBOCYTOPENIA 5URINE
>DISCOLOURATION 5VISION BLURRED 5ARTHRALGIA 4ARTHRITIS AGGRAVATED 4BOWEL
>OBSTRUCTION 4BRUISE 4BUN INCREASED 4CARCINOMA 4CONGESTIVE HEART FAILURE
>4CORONARY ARTERY OCCLUSION 4ESR INCREASED 4EYE HAEMORRHAGE 4HEPATIC
>FAILURE 4HIATUS HERNIA 4LEUKOCYTOSIS 4OEDEMA 4PANCREATITIS ACUTE
>4PARAESTHESIA 4POLYMYOSITIS 4SLEEP DISTURBED 4TACHYCARDIA 4ANAEMIA
>3ANEURYSM 3ANGINA UNSTABLE 3APPETITE LOST 3ARTERIOSCLEROSIS 3BULLOUS
>ERUPTION 3CARPAL TUNNEL SYNDROME 3CHEST TIGHTNESS OF 3CHOLECYSTITIS
>3COLON CARCINOMA 3DEPRESSION 3DIVERTICULITIS 3EFFICACY, LACK OF
>3EPIGASTRIC PAIN NOT FOOD-RELATED 3EYELID OEDEMA 3GASTRO-INTESTINAL
>DISORDER NOS 3GASTROINTESTINAL TRACT BLEED NOS 3GYNAECOMASTIA 3HDL
>DECREASED 3HEARTBURN 3HOARSENESS 3INFECTION LOCALISED 3LACTIC
>DEHYDROGENASE ACTIVITY INC 3LIPID METABOLISM DISORDER NOS 3MACULAR
>DEGENERATION 3MEMORY LOSS 3OEDEMA PERIORBITAL 3PANCYTOPENIA 3PLEURAL
>EFFUSION 3POST-OPERATIVE WOUND INFECTION 3PROTEINURIA 3PULMONARY OEDEMA
>3RBC DECREASED 3RENAL CALCULUS 3RENAL COLIC 3RETROSTERNAL PAIN
>3SWELLING NON-INFLAMMATORY 3SYNCOPE 3TIREDNESS 3UNCONSCIOUSNESS
>3URINARY FREQUENCY 3VASCULAR DISORDER 3ABDOMINAL PAIN LOWER 2ABDOMINAL
>PAIN UPPER 2ABSCESS 2ALOPECIA 2AMYLASE INCREASED 2ANAEMIA APLASTIC
>2ARRHYTHMIA 2ASTHMA 2BACK ACHE 2BALANCE DIFFICULTY 2BICARBONATE RESERVE
>DECREASED 2BLISTERS 2BLOATING 2BLOOD SUGAR DECREASED 2BONE DISORDER
>2BONE PAIN 2BRADYCARDIA 2BREAST CANCER 2BURN 2CANDIDIASIS
>2CARDIOMYOPATHY 2CEREBRAL VASCULAR DISTURBANCE 2CHEST CONGESTION 2CHEST
>DISCOMFORT 2CHEST PRESSURE SENSATION OF 2CHILLS 2CHOLANGITIS
>2COAGULATION DISORDER 2COLITIS ULCERATIVE AGGRAVATED 2CONFUSION
>2CONJUNCTIVITIS 2CONSCIOUSNESS DECREASED 2CRAMPS 2CYST NOS 2DEHYDRATION
>2DELIRIUM 2DEPRESSION AGGRAVATED 2DIABETES MELLITUS AGGRAVATED
>2DUODENAL ULCER 2ECCHYMOSIS 2ECG ABNORMAL 2ELECTROLYTE ABNORMALITY
>2ENCEPHALITIS 2ENCEPHALOPATHY 2EPISTAXIS 2ERUCTATION 2FLATULENCE
>2FRACTURE PATHOLOGICAL 2GALL BLADDER DISORDER 2GALL BLADDER STONES
>2GASTROENTERITIS 2GI HAEMORRHAGE 2HAEMATOMA 2HAEMATURIA 2HAEMORRHAGE
>NOS 2HAIR LOSS 2HEART DISORDER 2HEPATIC FUNCTION ABNORMAL 2HEPATITIS
>CHOLESTATIC 2HEPATOMEGALY 2HYDRONEPHROSIS 2HYPOCALCAEMIA 2HYPOGLYCAEMIA
>2HYPOPROTEINAEMIA 2HYPOXIA 2KIDNEY STONE 2LACTATE BLOOD INCREASE 2LOWER
>RESP. TRACT INFECTION 2MEDICATION ERROR 2MENORRHAGIA 2METASTASES NOS
>2MOUTH ULCERATION 2MOVEMENTS REDUCED 2MUSCLE DISCOMFORT 2MUSCLE
>TENDERNESS ANY SITE 2NAIL DISCOLOURATION 2NEUROPATHY 2NEUTROPENIA
>2NON-ACCIDENTAL OVERDOSE 2NUMBNESS 2NUMBNESS LOCALIZED 2OEDEMA OF
>EXTREMITIES 2OEDEMA PERIPHERAL 2OSTEOPOROSIS 2PAIN LEGS 2PROTHROMBIN
>TIME PROLONGED 2RASH MACULO-PAPULAR 2RASH SCALY 2RECTAL PROLAPSE 2RENAL
>FAILURE CHRONIC 2RENAL FUNCTION ABNORMAL 2RESPIRATORY DISORDER
>2RESPIRATORY DISTRESS 2RESPIRATORY DYSFUNCTION NOS 2RIGORS 2SEMEN
>ABNORMAL 2SEPSIS 2SERUM LIPID ABNORMAL NOS 2SHAKING 2SKIN
>DISCOLOURATION 2SKIN DISORDER 2SKIN DRY 2SKIN ULCERATION 2SLEEP
>DIFFICULT 2SLEEP DISORDER 2SMALL INTESTINE OBSTRUCTION 2SPEECH DISORDER
>2STRENGTH LOSS OF 2SUICIDE ATTEMPT 2SWALLOWING IMPAIRED 2TASTE
>ALTERATION 2TASTE PERVERSION 2TEMPERATURE ELEVATION 2THROAT SORE
>2THROAT SWELLING NON-SPECIFIC 2THROAT TIGHTNESS 2TOOTH DISORDER
>2TRANSIENT ISCHAEMIC ATTACK 2UPPER RESP TRACT INFECTION 2UREA BLOOD
>LEVEL INCREASED 2WEAKNESS VOLUNTARY MUSCLE 2ABDOMINAL DISCOMFORT
>1ABDOMINAL DISTENSION 1ACCIDENTAL OVERDOSE 1ACIDOSIS LACTIC 1ACIDOSIS
>METABOLIC 1ACNE 1AGITATION 1ALLERGIC CONJUNCTIVITIS 1ALLERGY 1ALP
>INCREASED 1ANAEMIA AGGRAVATED 1ANAEMIA HAEMOLYTIC 1ANAPHYLAXIS 1ANGER
>1ANGINAL ATTACK 1AORTIC ANEURYSM RUPTURE 1AORTIC STENOSIS 1AORTIC VALVE
>STENOSIS 1APPENDICITIS 1APPETITE INCREASED 1ARRHYTHMIA VENTRICULAR
>1ARTHRITIC-LIKE PAIN 1ASCITES 1ASTHENIA LEGS 1ATRIAL FLUTTER 1ATRIAL
>FLUTTER/ FIBRILLATION 1BACK DISCOMFORT 1BELCHING 1BILIARY COLIC
>1BILIRUBINAEMIA 1BLADDER CARCINOMA 1BLEEDING TIME INCREASED 1BLOOD
>PRESSURE DROP ARTERIAL 1BLOOD SEDIMENTATION INCREASED 1BLOOD UREA
>INCREASED 1BLOOD UREA NITROGEN INCREASED 1BONE NECROSIS 1BRAIN NEOPLASM
>MALIGNANT 1BREAST NEOPLASM FEMALE 1BREAST PAIN FEMALE 1BREAST PAIN MALE
>1BRONCHOSPASM 1BURNING MUCOSAL 1BURSITIS 1CALCIUM DEPOSITS 1CALCULUS
>URINARY BLADDER 1CERVICAL SMEAR TEST POSITIVE 1CERVIX CARCINOMA 1CHANGE
>IN BOWEL HABITS 1CHEST BURNING PAIN OF 1CHEST X-RAY ABNORMAL
>1CHOLESTASIS INTRAHEPATIC 1CHOLESTEROL BLOOD DECREASED 1CHOLESTEROL
>BLOOD REDUCED 1CHOLESTEROL SERUM INCREASED 1CIRRHOSIS BILIARY
>1CLAUDICATION INTERMITTENT 1COAGULATION TIME INCREASED 1COGNITIVE
>DISORDERS 1COMA 1CONFUSIONAL STATE 1CONGENITAL ANOMALY NOS 1CONGESTIVE
>CARDIAC FAILURE AGGR 1CONVULSIONS GRAND MAL 1CORNEAL OPACITY 1CORONARY
>ARTERY SPASM 1CORONARY DISEASE 1CRAMP ABDOMINAL 1CROHN'S DISEASE
>AGGRAVATED 1CRYING ABNORMAL 1CYANOSIS PERIPHERAL 1DEJECTION EMOTIONAL
>1DERMATOMYOSITIS 1DISCOMFORT BODILY 1DISORIENTATION 1DISSEM. INTRAVASC.
>COAGULATION 1DOWN'S SYNDROME 1DROWSINESS 1DRUG MALADMINISTRATION 1DRY
>EYES 1DRY LIPS 1DYSPHAGIA 1EAR ACHE 1ECG ABNORMALITIES NON-SPECIFIC
>1ECZEMA 1EIGHTH NERVE LESION NOS 1EMPHYSEMA 1ENDOMETRIAL ADENOCARCINOMA
>1EPIGLOTTITIS 1ERECTION DECREASED 1ERYTHROCYTOPENIA 1EXHAUSTION
>1EXTRASYSTOLE VENTRICULAR 1EXUDATE NIPPLES 1EYE INFECTION 1EYE PAIN
>1FACE OEDEMA 1FAECAL ABNORMALITY NOS 1FAECAL OCCULT BLOOD POSITIVE
>1FAECES DISCOLOURED 1FAECES PALE 1FATIGUE EXTREME 1FEELING COLD
>1FEELING HIGH 1FEELING OF WARMTH 1FIBRILLATION ATRIAL AGGRAVATED 1FLANK
>PAIN 1FLUSHING 1FORGETFULNESS 1FRACTURE RIB 1FRACTURE VERTEBRAL
>1GANGRENE 1GASTRIC CARCINOMA 1GASTRIC ULCER 1GENITAL NEOPLASM MALIGNANT
>MALE 1GINGIVITIS 1GLAUCOMA 1GLOTTIC OEDEMA 1GOUT 1HAEMATEMESIS
>1HAEMOPTYSIS 1HAEMORRHAGE BRAIN STEM 1HAEMORRHAGE NASAL 1HAIR THINNING
>1HEAD PRESSURE 1HEARING DECREASED 1HEART FAILURE 1HEART MALFORMATION
>1HEART MURMUR 1HEART POUNDING 1HEART THROBBING 1HEMIPARESIS 1HEPATIC
>CIRRHOSIS 1HEPATIC METASTASES 1HEPATIC NECROSIS 1HEPATIC NEOPLASM
>1HEPATIC STEATOSIS 1HEPATITIS FULMINANT 1HEPATITIS TOXIC
>1HEPATOCELLULAR DAMAGE 1HERNIA INGUINAL 1HIGH DENSITY LIPOPROTEIN
>DECREASE 1HIP DISLOCATION 1HIVES 1HOT FLUSHES 1HYPERBILIRUBINAEMIA
>1HYPERCHOLESTEROLAEMIA 1HYPERMAGNESAEMIA 1HYPERPARATHYROIDISM
>1HYPERPHOSPHATAEMIA 1HYPERTENSION AGGRAVATED 1HYPERVENTILATION
>1HYPOKALAEMIA 1HYPOMAGNESAEMIA 1HYPONATRAEMIA 1HYPOTHYROIDISM 1ILEUS
>PARALYTIC 1IMPOTENCE 1INCREASED INSULIN REQUIREMENT 1INDIGESTION
>1INFECTION BACTERIAL 1INFERTILITY MALE 1INFLICTED INJURY
>1INFLUENZA-LIKE SYMPTOMS 1INJECTION SITE REACTION 1IRRITABILITY
>1IRRITABLE BOWEL SYNDROME 1JOINT ACHE 1JOINT SWELLING NON-INFLAMMATORY
>1KIDNEY DYSFUNCTION 1LDH INCREASED SERUM 1LDL INCREASED 1LEG ULCER (EXC
>VARICOSE) 1LENTICULAR OPACITY 1LEUKAEMIA 1LIGHT-HEADED FEELING 1LIPASE
>INCREASED 1LIVER AND BILIARY SYSTEM DISORDERS 1LIVER FATTY 1LOW DENSITY
>LIPOPROTEIN INCREASED 1LUMBAR PAIN 1LYMPHOMA MALIGNANT 1MEMORY
>IMPAIRMENT 1MENIERE'S SYNDROME 1MIGRAINE 1MITRAL VALVE INCOMPETENCE
>1MOOD SWINGS 1MOUTH DRY 1MOUTH IRRITATION 1MULTIPLE MYELOMA 1MULTIPLE
>ORGAN FAILURE 1MUSCLE DEGENERATION 1MUSCLE DISORDER 1MUSCLE RIGIDITY
>1MUSCLE SPASTICITY 1MUSCLE STIFFNESS 1MUSCLE WASTING 1MUSCULO-SKELETAL
>SYSTEM DISORDERS 1MYOCARDIAL ISCHAEMIA 1NECROSIS ISCHAEMIC 1NEOPLASM
>1NEPHROTIC SYNDROME 1NERVOUSNESS 1NEURITIS 1NEUROLOGIC DISORDER NOS
>1NEUROPATHY PERIPHERAL 1NEUTROPHILIA 1NOCTURIA 1NON-HODGKIN'S LYMPHOMA
>1NOSEBLEED 1NPN INCREASED 1OEDEMA MOUTH 1OEDEMA PULMONARY 1OESOPHAGEAL
>VARICES 1OLIGOSPERMIA 1ORAL NEOPLASM BENIGN 1OVARIAN TUMOUR BENIGN
>1PAIN BURNING 1PAIN RIGHT UPPER QUADRANT 1PALLOR 1PANCREAS CARCINOMA
>1PANCREATITIS NECROTISING 1PANNICULITIS 1PARALYSIS 1PARALYSIS FACIAL
>1PASSED OUT 1PELVIC PAIN 1PERIODONTITIS 1PERIPHERAL GANGRENE
>1PERITONITIS 1PERSONALITY DISORDER 1PERSPIRATION EXCESSIVE 1PEYRONIE'S
>DISEASE 1PHLEBITIS 1PHOTOSENSITIVITY REACTION 1PLATELET PRODUCTION
>DECREASED 1PNEUMONIA LOBAR 1PNEUMONITIS 1POLYCYTHAEMIA 1POLYDIPSIA
>1POLYURIA 1POTASSIUM SERUM DECREASED 1POTASSIUM SERUM INCREASED
>1PRE-SYNCOPE 1PRICKING SKIN SENSATION 1PROSTATIC SPECIFIC ANTIGEN INCR.
>1PROSTATISM AGGRAVATED 1PSYCHIATRIC DISORDERS 1PULMONARY CONGESTION
>1PULMONARY FIBROSIS 1PULMONARY INFILTRATION 1PULSE RATE INCREASED
>1PULSE WEAK 1PYELONEPHRITIS 1PYLORIC ULCER 1PYOGENIC GRANULOMA
>1QUADRIPLEGIA 1RASH BULLOUS 1RASH ERYTHEMATOUS 1RASH PETECHIAL 1RASH
>PUSTULAR 1RECTAL BLEEDING 1RECTAL CARCINOMA 1RECURRENT CANCER 1RENAL
>CARCINOMA 1RENAL CYST 1RENAL FAILURE AGGRAVATED 1RESPIRATORY LESION
>1RESPIRATORY SYSTEM DISORDER 1RESTLESSNESS MARKED 1RHINITIS 1SCALP
>TENDERNESS 1SENSORY DISTURBANCE 1SEPTICAEMIA 1SERUM IRON DECREASED
>1SHIVERING 1SHIVERS 1SICK SINUS SYNDROME 1SKIN FLUSHED 1SKIN NECROSIS
>1SKIN NODULE 1SKIN REACTION LOCALISED 1SLEEP DECREASED 1SLEEPLESSNESS
>1SLURRED SPEECH 1SOMNOLENCE 1SPASMS 1SPINAL FRACTURES 1SPINE
>MALFORMATION 1SPLEEN DISORDER 1ST ELEVATED 1STEVENS JOHNSON SYNDROME
>1STOMACH UPSET 1STOMATITIS 1SUBARACHNOID HAEMORRHAGE 1SUGAR BLOOD LEVEL
>INCREASED 1SUGAR FASTING BLOOD LEVEL INCR 1SUICIDAL TENDENCY
>1SWALLOWING PAINFUL 1TENDINITIS 1TENDON INJURY 1TESTICULAR PAIN
>1THERAPEUTIC RESPONSE DECREASED 1THIRST 1THORACIC PAIN 1THROMBOSIS
>1THYROID CARCINOMA 1THYROID DISORDER 1TIA 1TINNITUS 1TOOTH
>DISCOLOURATION 1TREMOR 1URETHRAL CALCULUS 1URIC ACID BLOOD INCREASED
>1URINARY INCONTINENCE 1URINARY RETENTION 1URINE CONSTITUENTS ABNORMAL
>1URINE PRODUCTION SCANTY 1URTICARIA 1UTERINE CARCINOMA 1UTERINE FIBROID
>1UTERINE PROLAPSE 1UTEROVAGINAL PROLAPSE 1VAGINAL CANDIDIASIS 1VEIN
>VARICOSE 1VERTIGO 1VISION ABNORMAL 1VISUAL IMPAIRMENT 1VITAMIN B12
>DEFICIENCY 1
>
>CERIVASTATIN, 1.5 million, Off market in Aug, 2001 -
>(BAYCOL)(monograpgh not available)
>
>RHABDOMYOLYSIS 76CREATINE KINASE INCREASED 46MUSCLE PAIN 41WEAKNESS
>GENERALIZED 26MUSCLE WEAKNESS 25MYALGIA 24CPK INCREASED 22CREATINE
>PHOSPHOKINASE INCREASED 21SGOT INCREASED 18PAIN 16WALKING DIFFICULTY
>16BACK PAIN 14CREATININE BLOOD INCREASED 13LEG PAIN 13NAUSEA 13SGPT
>INCREASED 13RENAL FAILURE ACUTE 12FATIGUE 11MYOGLOBINURIA 11HEPATIC
>ENZYMES INCREASED 10MUSCLE ACHE 9MYOSITIS 9BREATH SHORTNESS 8DIARRHOEA
>8HEADACHE 8RENAL FAILURE NOS 8URINE DISCOLOURATION 8DIZZINESS 7LDH
>INCREASED 7PAIN NECK/SHOULDER 6VOMITING 6CHEST PAIN 5ANGINA PECTORIS
>4APPETITE DECREASED 4APPETITE LOST 4INFLUENZA-LIKE SYMPTOMS 4JOINT PAIN
>4JOINT STIFFNESS 4MALAISE 4MOBILITY DECREASED 4WEIGHT DECREASE
>4ASTHENIA LEGS 3BURNING SENSATION 3CARDIAC ARREST 3CONDITION AGGRAVATED
>3COUGHING 3FAECAL INCONTINENCE 3FALL 3ITCHING 3KIDNEY DYSFUNCTION
>3MUSCLE WASTING 3MYOPATHY 3PROTEINURIA 3RASH 3STROKE 3WEIGHT INCREASE
>3ABDOMINAL PAIN 2BLOOD SUGAR INCREASED 2BREATHING DIFFICULT 2BUN
>INCREASED 2CHEST DISCOMFORT 2CHILLS 2CRAMPS 2CRAMPS LEGS 2DYSPNOEA
>2ERYTHEMA 2EYE PAIN 2FATIGUE EXTREME 2FEVER 2FLANK PAIN 2HAEMATURIA
>2HEARTBURN 2HYPERKALAEMIA 2INSOMNIA 2JOINT INFLAMMATION 2LETHARGY
>2LEUCOPENIA 2MUSCLE ATROPHY 2MUSCLE CRAMP 2MUSCLE DEGENERATION 2MUSCLE
>DISORDER 2MUSCLE SPASTICITY 2NEUROPATHY PERIPHERAL 2NIGHTMARES
>2NUMBNESS 2NUMBNESS LOCALIZED 2OEDEMA PERIORBITAL 2PASSED OUT
>2POTASSIUM SERUM INCREASED 2RECTAL BLEEDING 2RENAL PAIN 2SINUSITIS
>2STOMACH UPSET 2SWEATING INCREASED 2TACHYCARDIA 2THROAT SWELLING
>NON-SPECIFIC 2VISION BLURRED 2ABDOMEN ENLARGED 1ABDOMINAL PAIN UPPER
>1ALKALINE PHOSPHATASE SERUM INCR 1ALLERGIC REACTION 1ALOPECIA 1AMBITION
>LOSS OF 1ANAPHYLACTIC SHOCK 1ANGINA PECTORIS AGGRAVATED 1ANGINA
>UNSTABLE 1ANXIETY 1APHONIA 1ARTHRALGIA 1ASCITES 1ASPHYXIA 1BACK ACHE
>1BACK DISCOMFORT 1BALANCE DIFFICULTY 1BILIRUBIN INCREASED 1BLACK-OUT
>(NOT AMNESIA) 1BLISTERS 1BLOOD UREA NITROGEN INCREASED 1BONE PAIN
>1BRADYCARDIA 1BRUISE 1BULLOUS ERUPTION 1CARDIAC ARRHYTHMIA NOS 1CARPAL
>TUNNEL SYNDROME 1CATARACT 1CEREBROVASCULAR DISORDER 1CHEST PRESSURE
>SENSATION OF 1CHEST TIGHTNESS OF 1CHOKING 1CHOLECYSTITIS 1CHOLESTEROL
>SERUM INCREASED 1CIRRHOSIS BILIARY 1COGNITIVE FUNCTION ABNORMAL
>1CONVULSIONS 1DEBILITY MARKED 1DEHYDRATION 1DEPRESSION 1DEPRESSION
>AGGRAVATED 1DIAPHORESIS 1DIGESTION IMPAIRED 1EAR RINGING 1ELECTROLYTE
>ABNORMALITY 1EMBOLISM LIMB 1EMOTIONAL LABILITY 1EPIGASTRIC PAIN NOT
>FOOD-RELATED 1ERECTION DECREASED 1EYE ABNORMALITY 1FACE OEDEMA
>1FASCIITIS 1FEELING UNWELL 1GAIT ABNORMAL 1GAMMA-GLUTAMYLTRANSFERASE
>INCR. 1GASTRITIS 1GASTROESOPHAGEAL REFLUX 1HEAD PAIN 1HEARING DECREASED
>1HEART DISORDER 1HEAVINESS IN LIMBS 1HEPATIC FAILURE 1HEPATITIS 1HIVES
>1HYPERGLYCAEMIA 1HYPERTONIA 1HYPERURICAEMIA 1HYPOTENSION 1HYPOXIA
>1INDIFFERENCE 1IRRITABILITY 1JAUNDICE 1KIDNEY STONE 1LARYNGEAL OEDEMA
>1LARYNGOSPASM 1LIVER ENLARGEMENT 1LIVER FUNCTION TESTS ABNORMAL NOS
>1LUMBAR DISC LESION 1MEDICATION ERROR 1MEMORY DISTURBANCE 1MENTAL
>DULLNESS 1MOVEMENTS REDUCED 1MUSCLE STIFFNESS 1MUSCLE TENDERNESS ANY
>SITE 1MUSCLE TONE FLACCID 1MUSCULO-SKELETAL SYSTEM DISORDERS
>1MYOCARDIAL INFARCTION 1OEDEMA 1OEDEMA LEGS 1OEDEMA PERIPHERAL
>1OLIGURIA 1OVARIAN CARCINOMA 1PAIN GROIN 1PAIN LEGS 1PALPITATION
>1PANCREAS CARCINOMA 1PARAESTHESIA 1PERIPHERAL ISCHAEMIA 1POLYARTHRITIS
>GENERALIZED 1POLYMYALGIA RHEUMATICA 1PRICKING SKIN SENSATION 1PRURITUS
>1PULSE IRREGULARITY NOS 1RED EYE 1RENAL FUNCTION ABNORMAL 1RENAL
>TUBULAR NECROSIS 1RESTLESSNESS MARKED 1SENSORY DISTURBANCE 1SKELETAL
>MALFORMATION 1SKELETAL PAIN 1SKIN COLD CLAMMY 1SLEEP DECREASED
>1SLEEPINESS 1SMELL CHANGE 1SPASMS 1STRENGTH LOSS OF 1SUFFOCATION
>FEELING 1SWALLOWING DIFFICULT 1SYNOVITIS 1TACHYCARDIA VENTRICULAR
>1TASTE LOSS 1THERAPEUTIC RESPONSE DECREASED 1THORACIC PAIN 1THROAT
>IRRITATION 1THROMBOCYTOPENIA 1THYROID DISORDER 1TINNITUS 1TIREDNESS
>1TONGUE DISORDER 1TONGUE INFLAMMATION 1TONGUE OEDEMA 1TONGUE SWELLING
>NON-SPECIFIC 1TREMOR 1UREA BLOOD LEVEL INCREASED 1URINARY TRACT
>INFECTION 1URINE ABNORMAL 1VASCULAR DISORDER 1VISION ABNORMAL 1VISION
>DECREASED 1WEAKNESS VOLUNTARY MUSCLE 1
>
>FLUVASTATIN, 1.5 million - (LESCOL) (monograph not available)
>
>EFFICACY, LACK OF 3FATIGUE 3MYOCARDIAL INFARCTION 3NAUSEA 3PANCREATITIS
>3PRURITUS 3RASH 3WEAKNESS GENERALIZED 3ANAEMIA 2DYSPNOEA 2FALL 2HAIR
>LOSS 2HEADACHE 2HEPATITIS CHOLESTATIC 2JAUNDICE 2LIPASE INCREASED
>2MOUTH DRY 2MUSCLE PAIN 2MUSCLE WEAKNESS 2SGPT INCREASED 2WEIGHT
>DECREASE 2ABDOMINAL PAIN 1ALLERGIC REACTION 1ALOPECIA 1ANGIOEDEMA
>1ANOREXIA 1APPETITE DECREASED 1ASTHENIA 1BILIRUBIN INCREASED
>1BILIRUBINURIA 1BRADYCARDIA 1CARDIAC ARREST 1CHEST PAIN 1CHILLS
>1CONVULSIONS 1CORONARY ARTERY OCCLUSION 1COUGHING 1CPK INCREASED
>1CRACKLES 1CREATINE KINASE INCREASED 1CREATININE BLOOD INCREASED
>1DEHYDRATION 1DROWSINESS 1DRUGGEDNESS 1ESR INCREASED 1FEELING UNWELL
>1FLUSHING 1FRACTURE PATHOLOGICAL 1GAMMA-GLUTAMYLTRANSFERASE INCR.
>1GAMMA-GT INCREASED 1HAEMATOMA 1HEPATIC FAILURE 1HEPATITIS 1HIGH
>DENSITY LIPOPROTEIN DECREASE 1HYPERCHOLESTEROLAEMIA 1HYPERGLYCAEMIA
>1HYPOAESTHESIA 1HYPOTENSION 1INTRAOCULAR PRESSURE INCREASED 1ITCHING
>1LEUCOPENIA 1LIPS SWELLING NON-SPECIFIC 1LUPUS ERYTHEMATOSUS SYSTEMIC
>1MUSCLE ACHE 1MUSCLE CRAMP 1MYALGIA 1MYOPATHY 1MYOSITIS 1NEUROPATHY
>PERIPHERAL 1NUMBNESS 1OEDEMA LEGS 1OEDEMA PULMONARY 1PARAESTHESIA
>1PHOSPHATASE ALKALINE INCREASED 1PNEUMONIA 1RASH ERYTHEMATOUS 1RENAL
>FAILURE NOS 1SCLERAL DISCOLOURATION 1SGOT INCREASED 1SHAKING 1SYNCOPE
>1TIREDNESS 1UNCONSCIOUSNESS 1URINE DISCOLOURATION 1URTICARIA 1VOMITING
>1WHEEZES 1
>
>LOVASTATIN, 2.8 million - (MEVACOR) (no monograph available)
>
>MYALGIA 17NAUSEA 11HEPATIC ENZYMES INCREASED 10CREATINE PHOSPHOKINASE
>INCREASED 9RHABDOMYOLYSIS 8ABDOMINAL PAIN 7DIZZINESS 7MUSCLE WEAKNESS
>7CHEST PAIN 6CREATININE BLOOD INCREASED 6HEADACHE 6PRURITUS 6SGOT
>INCREASED 6ASTHENIA 5CREATINE KINASE INCREASED 5JAUNDICE 5MYOPATHY
>5MYOSITIS 5RASH 5VOMITING 5BILIRUBINAEMIA 4CONFUSION 4FATIGUE 4FEVER
>4HAIR LOSS 4HEPATIC FUNCTION ABNORMAL 4HEPATITIS 4ITCHING 4MUSCLE ACHE
>4MYOCARDIAL INFARCTION 4VISION BLURRED 4ALLERGIC REACTION 3CARCINOMA
>3COUGHING 3DEPRESSION 3DIARRHOEA 3DYSPNOEA 3HAEMATURIA 3IMPOTENCE
>3INSOMNIA 3MUSCLE CRAMP 3MUSCLE PAIN 3MYOGLOBINURIA 3PAIN 3PHOSPHATASE
>ALKALINE INCREASED 3RENAL FAILURE ACUTE 3RESPIRATORY INSUFFICIENCY
>3WEAKNESS GENERALIZED 3ABDOMINAL PAIN UPPER 2ALOPECIA 2ANGINA PECTORIS
>AGGRAVATED 2ANOREXIA 2BILIRUBIN INCREASED 2BLOOD IN STOOL 2CONDITION
>AGGRAVATED 2CPK INCREASED 2ESR INCREASED 2EYE PAIN 2FACE OEDEMA 2FAECES
>PALE 2GAMMA-GLUTAMYLTRANSFERASE INCR. 2GI HAEMORRHAGE 2HEART DISORDER
>2HEPATIC FAILURE 2JAUNDICE CHOLESTATIC 2LDH INCREASED SERUM 2LEG PAIN
>2MOVEMENTS REDUCED 2MUSCLE STIFFNESS 2NEUTROPENIA 2OEDEMA PERIORBITAL
>2PANCREATITIS 2PANCYTOPENIA 2PARAESTHESIA 2PROTEINURIA 2RASH
>ERYTHEMATOUS 2RASH MACULO-PAPULAR 2RESPIRATORY DISORDER 2SEXUAL
>FUNCTION ABNORMAL 2SGPT INCREASED 2SWEATING INCREASED 2URINE
>DISCOLOURATION 2VISION ABNORMAL 2ALKALINE PHOSPHATASE SERUM INCR
>1AMNESIA 1ANAEMIA 1ANEURYSM 1ANGINA PECTORIS 1ANGIONEUROTIC OEDEMA
>1ANXIETY 1APATHY 1APPETITE DECREASED 1ARTERITIS 1ARTHRALGIA 1ASYSTOLIA
>1ATAXIA 1BALANCE DIFFICULTY 1BLADDER CARCINOMA 1BLOATING 1BLOOD IN
>URINE 1BLOOD UREA NITROGEN INCREASED 1BREAST PAIN FEMALE 1CARCINOMA
>SQUAMOUS 1CATARACT 1CEREBRAL INFARCTION 1CHEST PAIN PRECORDIAL 1CHEST
>TIGHTNESS OF 1CHLOASMA 1CHOLESTASIS INTRAHEPATIC 1COLITIS ULCERATIVE
>1CORNEAL OPACITY 1CORONARY DISEASE 1CRAMPS LEGS 1CYST NOS 1DEPRESSED
>STATE 1DEPRESSION AGGRAVATED 1DERMATITIS 1DROWSINESS 1DRUG LEVEL
>INCREASED 1DYSPHAGIA 1DYSPHASIA 1EAR PAIN 1ECG ABNORMAL 1ENCEPHALOPATHY
>1EOSINOPHILIC GRANULOMA 1EPISTAXIS 1ERUPTION 1ERYTHEMA 1EXHAUSTION 1EYE
>ABNORMALITY 1FAECES DISCOLOURED 1FAINTNESS 1FALL 1FAT TISSUE INCREASED
>1FIBRILLATION ATRIAL 1FRACTURE PATHOLOGICAL 1GAIT UNSTEADY 1GASTRIC
>ACID DECREASED 1HAEMORRHAGE NOS 1HEARTBURN 1HEPATIC DISEASE 1HEPATIC
>NECROSIS 1HEPATOMEGALY 1HEPATOTOXIC EFFECT 1HIVES 1HOT FLUSHES
>1HYPERTENSION 1HYPERTHYROIDISM 1HYPOAESTHESIA 1HYPOCHLORAEMIA
>1HYPONATRAEMIA 1IRITIS 1IRRITABILITY 1JOINT PAIN 1JOINT STIFFNESS 1LDH
>INCREASED 1LE RASH 1LE SYNDROME 1LEUCOPENIA 1LIBIDO DECREASED 1LIVER
>TENDER 1MALAISE 1MELAENA 1MEMORY IMPAIRMENT 1MICTURITION DISORDER
>1MIGRAINE 1MOUTH DRY 1MUSCLE ATROPHY 1MUSCLE DISORDER 1MUSCLE RIGIDITY
>1MUSCLE SPASTICITY 1MYELITIS TRANSVERSE 1MYELOPATHY 1NAIL DISORDER
>1NERVOUSNESS 1NEUROPATHY 1NEUROTOXICITY 1NYSTAGMUS 1OEDEMA GENERALISED
>1OEDEMA GENITAL 1OESOPHAGOSPASM 1OLIGURIA 1PALLOR 1PARANOID REACTION
>1PERSONALITY DISORDER 1PHARYNGITIS 1PLEURAL EFFUSION 1PLEURISY
>1PNEUMONIA 1PROTHROMBIN TIME PROLONGED 1PULSE RATE INCREASED 1PURPURA
>1RAYNAUD'S PHENOMENON 1RENAL FUNCTION ABNORMAL 1RETINAL DISORDER
>1SEPSIS 1SKIN DISORDER 1SKIN DRY 1SKIN ERYTHEMA DESQUAMATIVE 1SKIN
>ULCERATION 1SLEEP DISORDER 1SOMNOLENCE 1SPASMS 1SPEECH DISORDER 1SPINAL
>CORD COMPRESSION 1SPUTUM INCREASED 1TASTE PERVERSION 1TENDINITIS
>1THERAPEUTIC RESPONSE DECREASED 1THROMBOCYTOPENIA 1TINGLING SKIN
>1TINNITUS 1TREMOR 1TREMOR LIMB 1URINARY INCONTINENCE 1URINE ABNORMAL
>1URTICARIA 1VEIN DISORDER 1VERTIGO 1VISION DECREASED 1VISUAL FIELD
>DEFECT 1WALKING DIFFICULTY 1WEAKNESS VOLUNTARY MUSCLE 1
>
>PRAVASTATIN, 9.2 million (PRAVACHOL) (monograph)
>
>NAUSEA 11CREATINE PHOSPHOKINASE INCREASED 9FATIGUE 9ABDOMINAL PAIN
>8MUSCLE WEAKNESS 8MUSCLE PAIN 7MYALGIA 7RASH 7CHEST PAIN 6CREATINE
>KINASE INCREASED 6HEADACHE 6HEPATITIS 6LDH INCREASED 6PRURITUS
>6VOMITING 6WEAKNESS GENERALIZED 6CREATININE BLOOD INCREASED 5DIZZINESS
>5HEPATIC ENZYMES INCREASED 5MUSCLE ACHE 5RHABDOMYOLYSIS 5SGOT INCREASED
>5ALKALINE PHOSPHATASE SERUM INCR 4INSOMNIA 4JAUNDICE 4PAIN 4RASH
>ERYTHEMATOUS 4URINE DISCOLOURATION 4WALKING DIFFICULTY 4WEIGHT DECREASE
>4ANOREXIA 3ASTHENIA 3CONDITION AGGRAVATED 3DIARRHOEA 3DYSPNOEA 3FACE
>OEDEMA 3FAECES DISCOLOURED 3FEVER 3GASTRO-INTESTINAL DISORDER NOS
>3IMPOTENCE 3ITCHING 3LETHARGY 3MALAISE 3MYOSITIS 3NIGHTMARES 3SGPT
>INCREASED 3THERAPEUTIC RESPONSE DECREASED 3VISION BLURRED 3ARRHYTHMIA
>2ARTHRALGIA 2BALANCE DIFFICULTY 2BILIRUBIN INCREASED 2BREATH SHORTNESS
>2BUN INCREASED 2CATARACT 2CONJUNCTIVITIS 2CONSTIPATION 2DYSPEPSIA
>2EPIGASTRIC PAIN NOT FOOD-RELATED 2EPISTAXIS 2ERYTHEMA 2ESR INCREASED
>2HAIR TEXTURE ABNORMAL 2HIVES 2HYPERGLYCAEMIA 2HYPOTENSION 2JOINT PAIN
>2LUPUS ERYTHEMATOSUS SYSTEMIC 2MUSCLE CRAMP 2MYOCARDIAL INFARCTION
>2NEPHRITIS 2NUMBNESS LOCALIZED 2PAIN LEGS 2PANCREATITIS 2PETECHIAE
>2PHOTOSENSITIVITY REACTION 2PNEUMONIA 2POLYURIA 2PULMONARY CARCINOMA
>2PULMONARY FIBROSIS 2RENAL FAILURE ACUTE 2SWEATING INCREASED 2TINGLING
>SKIN 2TINNITUS 2TONGUE OEDEMA 2URTICARIA 2VERTIGO 2VISION ABNORMAL
>2VISION DECREASED 2ABDOMINAL DISCOMFORT 1ACCOMMODATION ABNORMAL
>1ACIDOSIS LACTIC 1ACNE 1ALLERGIC REACTION 1ANAEMIA APLASTIC 1ANAEMIA
>MICROCYTIC 1ANAPHYLACTIC SHOCK 1ANKLE OEDEMA 1ANTINUCLEAR FACTOR TEST
>POSITIVE 1ANXIETY 1APPETITE ABSENT 1ASCITES 1ATAXIA 1ATRIAL FLUTTER/
>FIBRILLATION 1AURA 1BICARBONATE RESERVE DECREASED 1BILIRUBINAEMIA
>1BLADDER CARCINOMA 1BLINDNESS 1BLISTERS 1BLOOD IN URINE 1BREAST
>ENLARGEMENT MALE 1BREAST NEOPLASM MALIGNANT FEMALE 1BREAST PAIN MALE
>1BULLOUS ERUPTION 1BURNING SENSATION 1BURSITIS 1CHILLS 1CONFUSION
>1CONGESTIVE HEART FAILURE 1CONJUNCTIVAL DISCOLOURATION 1CONSCIOUSNESS
>DECREASED 1COUGHING 1CPK INCREASED 1CRAMP ABDOMINAL 1CRAMPS LEGS
>1CRYOGLOBULINAEMIA 1DEPRESSED STATE 1DEPRESSION 1DERMATITIS 1DIABETES
>MELLITUS 1DIPLOPIA 1DISORIENTATION 1DREAMING ABNORMAL 1EXHAUSTION 1EYE
>HAEMORRHAGE 1EYE IRRITATION 1EYE PAIN 1EYELID OEDEMA 1FAECES PALE 1FALL
>1FEELING UNWELL 1GAMMA-GT INCREASED 1GASTROESOPHAGEAL REFLUX 1GI
>NEOPLASM BENIGN 1GINGIVAL BLEEDING 1GINGIVAL HYPERTROPHY 1GOUT
>AGGRAVATED 1GYNAECOMASTIA 1HAEMATURIA 1HAIR LOSS 1HALLUCINATION VISUAL
>1HEARING DECREASED 1HEPATITIS CHOLESTATIC 1HOT FLUSHES
>1HYPERCHOLESTEROLAEMIA 1HYPERLIPAEMIA 1HYPOXIA 1INDIGESTION 1INFECTION
>1INFLUENZA-LIKE SYMPTOMS 1INTELLECT IMPAIRED 1JOINT ACHE 1JOINT
>DYSFUNCTION 1JOINT INFLAMMATION 1LACTATE BLOOD INCREASE 1LEG PAIN
>1LEUCOPENIA 1LEUKOCYTOSIS 1LIBIDO DECREASED 1LIVER FATTY 1LIVER
>FUNCTION TESTS ABNORMAL NOS 1LIVER TENDER 1LOWER RESP. TRACT INFECTION
>1MENSES ONSET DELAYED 1MENTATION IMPAIRED 1MICTURITION FREQUENCY 1MOOD
>SWINGS 1MUSCLE DISORDER 1MUSCLE RIGIDITY 1MUSCLE SPASTICITY 1MUSCLE
>STIFFNESS 1MUSCLE WASTING 1MYELOFIBROSIS 1MYELOPROLIFERATIVE DISORDER
>1NAIL DISCOLOURATION 1NEPHRITIS INTERSTITIAL 1NERVOUSNESS 1NEUROPATHY
>PERIPHERAL 1NUMBNESS 1PAIN GROIN 1PALPITATION 1PARAESTHESIA
>1PHARYNGITIS 1PHOTOSENSITIVITY TOXIC REACTION 1PLEURAL PAIN 1PNEUMONIA
>LOBAR 1POLYMYALGIA RHEUMATICA 1POTASSIUM SERUM INCREASED 1PROTEINURIA
>1PRURITUS ANI 1PSORIASIS 1PSORIASIS AGGRAVATED 1PURPURA ALLERGIC 1RASH
>MACULO-PAPULAR 1RENAL FUNCTION ABNORMAL 1RENAL SCLEROSIS 1SCOTOMA
>1SEBORRHOEA 1SEPSIS SECONDARY 1SKIN DISCOLOURATION 1SKIN DRY 1SLEEP
>DISTURBED 1SLEEP RESTLESS 1STAGGERING GAIT 1STOMACH UPSET 1SUBGLOTTIC
>OEDEMA 1SUICIDAL TENDENCY 1SUICIDE 1SUICIDE ATTEMPT 1SWELLING
>NON-INFLAMMATORY 1SWOLLEN ABDOMEN 1TASTE ALTERATION 1TASTE BITTER
>1TASTE LOSS 1TASTE METALLIC 1THROMBOCYTOPENIA 1THROMBOSIS VENOUS DEEP
>1TIREDNESS 1UNCONSCIOUSNESS 1URINARY CASTS 1URINE FLOW DECREASED
>1VISION DISORDERS 1WHEALS 1
>
>ROSUVASTATIN, 0.4 million - (CRESTOR) (no monograph available)
>
>ABDOMINAL PAIN 5MUSCLE PAIN 5ITCHING 4MUSCLE ACHE 4BLOOD IN URINE
>3DIZZINESS 3SGOT INCREASED 3ALLERGIC REACTION 2BILIRUBIN INCREASED
>2CREATININE BLOOD INCREASED 2ERYTHEMA 2HEADACHE 2LDH INCREASED 2MUSCLE
>WEAKNESS 2MYALGIA 2NAUSEA 2NEPHROPATHY NOS 2OEDEMA 2OEDEMA PERIPHERAL
>2PANCREATITIS 2PROTEINURIA 2RASH 2SGPT INCREASED 2SWEATING INCREASED
>2VOMITING 2WEAKNESS GENERALIZED 2ABDOMINAL DISTENSION 1ACNE 1ALKALINE
>PHOSPHATASE SERUM INCR 1ANAEMIA HAEMOLYTIC 1ANAEMIA NORMOCYTIC
>1ANGIOEDEMA 1APHONIA 1ARTHRALGIA 1BACK PAIN 1BLINDNESS TEMPORARY
>1BLOATING 1BLOOD PRESSURE INCREASED 1BLOOD SUGAR INCREASED 1BRADYCARDIA
>1BREAST ENGORGEMENT 1BURNING SENSATION 1CARPAL TUNNEL SYNDROME 1CHEST
>PAIN 1CONDITION AGGRAVATED 1COOMBS DIRECT TEST POSITIVE 1COUGHING 1CPK
>INCREASED 1CRAMPS 1CREATINE KINASE INCREASED 1DIARRHOEA 1DIVERTICULITIS
>1DYSPEPSIA 1DYSPNOEA 1ECG ABNORMAL SPECIFIC 1EYE ABNORMALITY 1EYE
>IRRITATION 1FEELING UNWELL 1FEVER 1GAMMA-GT INCREASED 1GUILLAIN-BARRE
>SYNDROME 1HAEMATURIA 1HEART DISORDER 1HEART FLUTTERING 1HYPERTHYROIDISM
>1INFLUENZA-LIKE SYMPTOMS 1INSOMNIA 1INTRAOCULAR PRESSURE INCREASED 1JAW
>STIFFNESS 1JOINT PAIN 1LACRIMATION ABNORMAL 1MIGRAINE 1MUSCLE CRAMP
>1MUSCLE RIGIDITY 1MYOCARDIAL INFARCTION 1MYOSITIS 1NAIL DISORDER
>1OEDEMA LEGS 1PAIN 1PAIN LEGS 1PALPITATION 1PEPTIC ULCER 1PETECHIAE
>1PETECHIAE ORAL MUCOSA 1PROTHROMBIN TIME PROLONGED 1PRURITUS 1PULSE
>RATE INCREASED 1RASH MACULO-PAPULAR 1RENAL FAILURE ACUTE 1SALIVA VISCID
>1SKIN PEELING 1SUGAR BLOOD LEVEL INCREASED 1THROAT SORE
>1THROMBOCYTOPENIA 1TINGLING SKIN 1TREMOR 1UNCONSCIOUSNESS 1URINE
>DISCOLOURATION 1URTICARIA 1VASCULITIS 1VENOUS THROMBOSIS 1VISION DOUBLE
>1
>
>SIMVASTATIN - 12.4 million (ZOCOR) (monograph)
>
>CREATINE KINASE INCREASED 17MUSCLE PAIN 17MYALGIA 16CREATINE
>PHOSPHOKINASE INCREASED 14NAUSEA 14FATIGUE 13DIZZINESS 11MUSCLE
>WEAKNESS 11MYOCARDIAL INFARCTION 11MUSCLE ACHE 10RHABDOMYOLYSIS 10SGOT
>INCREASED 10SGPT INCREASED 10VISION BLURRED 10CREATININE BLOOD
>INCREASED 9HEADACHE 9CHEST PAIN 8DIARRHOEA 8VOMITING 8HEPATITIS 6PAIN
>6RASH 6ARTHRALGIA 5BILIRUBIN INCREASED 5JOINT PAIN 5LEG PAIN 5MUSCLE
>CRAMP 5PAIN LEGS 5WEAKNESS VOLUNTARY MUSCLE 5ABDOMINAL PAIN 4ALKALINE
>PHOSPHATASE SERUM INCR 4ANOREXIA 4CONDITION AGGRAVATED 4CPK INCREASED
>4DYSPNOEA 4HAIR LOSS 4LEUKOCYTOSIS 4LIGHT-HEADED FEELING 4MALAISE
>4MYOPATHY 4NUMBNESS LOCALIZED 4PAIN NECK/SHOULDER 4PALPITATION
>4PROTEINURIA 4PRURITUS 4WALKING DIFFICULTY 4WEAKNESS GENERALIZED
>4WEIGHT DECREASE 4ADENOCARCINOMA NOS 3ALOPECIA 3ANGINA PECTORIS
>AGGRAVATED 3BACK PAIN 3BREATH SHORTNESS 3CHILLS 3DEPRESSION 3FEVER
>3HAEMATURIA 3JAUNDICE 3JOINT STIFFNESS 3LETHARGY 3MUSCLE DISCOMFORT
>3NIGHTMARES 3OEDEMA LEGS 3RENAL FAILURE ACUTE 3SEPSIS 3SWEATING
>INCREASED 3UREA BLOOD LEVEL INCREASED 3URINE DISCOLOURATION 3ALLERGIC
>REACTION 2ANAEMIA 2ANEURYSM 2ANGINA PECTORIS 2ANTINUCLEAR FACTOR TEST
>POSITIVE 2ANXIETY 2APPETITE DECREASED 2ASTHENIA 2BONE PAIN 2COLON
>CARCINOMA 2CONSCIOUSNESS DECREASED 2CONSTIPATION 2CONVULSIONS 2CRAMPS
>LEGS 2DERMATITIS 2ECG ABNORMAL 2ERYTHEMA 2ESR INCREASED 2EYE IRRITATION
>2FALL 2FLATULENCE 2FRACTURE PATHOLOGICAL 2GAMMA-GLUTAMYLTRANSFERASE
>INCR. 2GASTRO-INTESTINAL DISORDER NOS 2HEPATIC ENZYMES INCREASED
>2HEPATIC NEOPLASM MALIGNANT 2HYPOTHYROIDISM 2INSOMNIA 2INTESTINAL
>FISTULA 2ITCHING 2JAUNDICE CHOLESTATIC 2LIPS SWELLING NON-SPECIFIC
>2MACULAR DEGENERATION 2MULTIPLE ORGAN FAILURE 2MYOSITIS 2OEDEMA 2OEDEMA
>OF EXTREMITIES 2PANCREATITIS NECROTISING 2PHOSPHATASE ALKALINE
>INCREASED 2PLEURAL EFFUSION 2POLYMYALGIA RHEUMATICA 2POTASSIUM SERUM
>INCREASED 2SINUSITIS 2THROMBOSIS 2URTICARIA 2VASCULITIS 2ABDOMINAL
>DISCOMFORT 1ABSCESS 1ACIDOSIS 1AKINESIA 1AMYLASE INCREASED
>1ANAPHYLACTIC REACTION 1ANGINA UNSTABLE 1ANGIOEDEMA 1ANOSMIA 1APPETITE
>LOST 1ARTERIAL BLOOD PRESSURE DECREASED 1ARTHRITIS AGGRAVATED
>1ATHEROSCLEROSIS 1ATRIAL FIBRILLATION PAROXYSMAL 1BLOOD IN URINE 1BLOOD
>PRESSURE INCREASED 1BLOOD SUGAR INCREASED 1BLOOD UREA DECREASED 1BODY
>ODOUR 1BONE METASTASES 1BOWEL PERFORATION 1BRAIN METASTASES 1BREAST
>NEOPLASM BENIGN FEMALE 1BREAST NEOPLASM FEMALE 1BREAST TENDERNESS
>1BRONCHITIS 1BRUISE 1BULLOUS ERUPTION 1BUN INCREASED 1CALF PAIN
>1CARDIOMYOPATHY 1CARDIOVASCULAR DISORDERS, GENERAL 1CATARACT
>1CELLULITIS 1CEREBROVASCULAR DISORDER 1CHANGE IN BOWEL HABITS 1CHEST
>DISCOMFORT 1CHEST X-RAY ABNORMAL 1CHRONIC OBSTRUCT AIRWAYS DISEASE
>1CLUBFOOT 1CONGENITAL ANOMALY NOS 1CONJUNCTIVAL HAEMORRHAGE 1CORONARY
>ARTERY DISORDER 1CORONARY ARTERY OCCLUSION 1COUGHING 1CRAMP ABDOMINAL
>1DEATH 1DEPRESSED STATE 1DIABETES MELLITUS 1DREAMING ABNORMAL 1DRUG -
>FOOD INTERACTION 1DYSAESTHESIA 1DYSPEPSIA 1DYSURIA 1EFFICACY, LACK OF
>1EMBOLISM ARTERIAL 1ENCEPHALOPATHY 1EOSINOPHILIA 1ERECTION DECREASED
>1ERYTHEMA MULTIFORME 1EYE PAIN 1FACE OEDEMA 1FAECES PALE 1FATIGUE
>EXTREME 1FEELING OF WARMTH 1FEELING UNWELL 1FOLATE SERUM TEST ABNORMAL
>1GAMMA-GT INCREASED 1GASTROESOPHAGEAL REFLUX 1GASTROINTESTINAL TRACT
>BLEED NOS 1GLOMERULONEPHRITIS 1GYNAECOMASTIA 1HAEMORRHAGE INTRACRANIAL
>1HAEMORRHOIDS 1HAIR TEXTURE ABNORMAL 1HEARING DECREASED 1HEART FAILURE
>1HEARTBURN 1HEPATIC FAILURE 1HEPATIC NECROSIS 1HEPATITIS CHRONIC ACTIVE
>1HEPATITIS TOXIC 1HEPATOMEGALY 1HIRSUTISM 1HYPERCHOLESTEROLAEMIA
>1HYPERKALAEMIA 1HYPERTENSION 1HYPOCHLORAEMIA 1HYPOGLYCAEMIA
>1HYPONATRAEMIA 1HYPOREFLEXIA 1HYPOTENSION 1IMMUNOGLOBULINS INCREASED
>1IMPOTENCE 1INFECTION LOCALISED 1INFECTION SUSCEPTIBILITY INCR
>1INFECTION VIRAL 1INFLUENZA-LIKE SYMPTOMS 1INTESTINAL PERFORATION
>1INTRAOCULAR PRESSURE INCREASED 1ISCHAEMIA PERIPHERAL 1JERKY MOVEMENT
>NOS 1KERATOSIS 1LDH INCREASED 1LDH INCREASED SERUM 1LE SYNDROME 1LIBIDO
>DECREASED 1LOWER RESP. TRACT INFECTION 1LYMPHOPENIA 1MEMORY DISTURBANCE
>1MEMORY LOSS 1METABOLIC AND NUTRITIONAL DISORDERS 1MOUTH DRY 1MUSCLE
>ATROPHY 1MUSCLE DISORDER 1MUSCLE RIGIDITY 1MUSCLE SPASTICITY 1MUSCLE
>STIFFNESS 1MUSCLE WASTING 1MYOCARDIAL ISCHAEMIA 1MYOGLOBINURIA 1NAIL
>DISORDER 1NASAL CONGESTION 1NEOPLASM 1NEOPLASM NOS 1NEPHROLITHIASIS
>1NEUROLOGIC DISORDER NOS 1NEUROPATHY 1NEUROPATHY PERIPHERAL 1NOCTURIA
>1NOSEBLEED 1NUMBNESS 1NYSTAGMUS 1OEDEMA CEREBRAL 1OEDEMA PERIPHERAL
>1OLIGURIA 1OVARIAN CYST 1OVARIAN DISORDER 1PAIN GROIN 1PANCREAS
>CARCINOMA 1PANCREATITIS ACUTE 1PARAESTHESIA 1PERIPHERAL GANGRENE
>1PHOTOPHOBIA 1PLASMA OSMOLALITY DECREASED 1PNEUMONIA 1PROSTATIC
>DISORDER 1PSORIASIS AGGRAVATED 1PSYCHOSIS 1PSYCHOSIS AGGRAVATED
>1PULMONARY CARCINOMA 1PULSE RATE INCREASED 1PURPURA 1RASH ERYTHEMATOUS
>1RASH MACULO-PAPULAR 1RASH PURPURIC 1RENAL FAILURE NOS 1RESPIRATORY
>DISORDER 1RETINAL VASCULAR DISORDER NOS 1RIGORS 1SALIVA DECREASED
>1SCHIZOPHRENIC REACTION 1SHAKING 1SKIN HYPERPIGMENTATION 1SLEEP
>DECREASED 1SLEEP DISTURBED 1SPASMS 1STOMACH UPSET 1SUGAR BLOOD LEVEL
>INCREASED 1SWELLING NON-INFLAMMATORY 1TACHYCARDIA SUPRAVENTRICULAR
>1TASTE LOSS 1TASTE PERVERSION 1TENDON INJURY 1THERAPEUTIC RESPONSE
>DECREASED 1THROAT SORE 1THROAT TIGHTNESS 1THROMBOCYTOPENIA
>1THROMBOCYTOSIS 1THYROID CYST 1THYROID ENLARGED 1TINNITUS 1TIRED EYE
>1TIREDNESS 1UNCONSCIOUSNESS 1URINARY FREQUENCY 1URINARY INCONTINENCE
>1URINARY TRACT INFECTION 1URINE VOLUME DEFICIENT 1UTERINE FIBROID
>1VERTIGO 1VESICULAR ERUPTION 1VESICULAR RASH 1VISION DECREASED 1VISUAL
>DISTURBANCE 1VOMITING BLOOD 1WEIGHT INCREASE 1

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