Re: drugs that deplete coq10
From: Sharon Hope (shope_at_anet.net)
Date: 02/03/05
- Next message: Sharon Hope: "Researchers find Diabetes trigger, implications in heart disease"
- Previous message: Sharon Hope: "Re: More statin adverse effects to become obvious?"
- In reply to: Zee: "Re: drugs that deplete coq10"
- Next in thread: adam_becker_sr_at_yahoo.com: "Re: drugs that deplete coq10"
- Messages sorted by: [ date ] [ thread ]
Date: Wed, 2 Feb 2005 20:50:22 -0800
Has anyone seen a rating for NOW brand CoQ10?
They make a 400mg capsule that is much more convenient when the theraputic
dosage is 800-1200 mg/day.
"Zee" <zwalanga@yahoo.com> wrote in message
news:1107384500.575471.85390@c13g2000cwb.googlegroups.com...
> Helpful information on quantity and quality and approved brands of
> coq10. More on subscription.
>
> http://www.consumerlabs.com/results/CoQ10.asp
>
> Zee
>
>
>
> Zee wrote:
>> Statins, Dymelor, Micronase and Tolinase deplete coq10
>> Glucophage depletes coq10 and B12
>> Adapin, Aventyl, Elavil, Tofranil, Pamelor, Sinequan and Norpramin
>> Elavil and some pain killers prescribed for peripheal neuropathy
>>
>> ~~~~~~~~~~~~~~~~~~
>>
>>
>>
>>
>> 02/02/05
>>
>> Ken Baker Column
>>
>> Are the risks of nutrient depletion by statins excessive?
>>
>> Maintenance of healthy heart, nerve, brain, liver, and skeletal
> muscles
>> requires CoQ10. Deficiencies have reportedly given rise to congestive
>> heard failure, weakening of the heart muscles, attention problems,
>> delayed reflexes, cognitive decline and memory impairment. There is
> no
>> serious debate, CoQ10 is absolutely essential to the conversion
> inside
>> each cell of nutrients and oxygen to energy. Don't leave home without
>> it.
>>
>> Last week we reviewed how Walter, a reader of this column, avoided
> the
>> statin drug, Lipitor, by letting food be his medicine. That, coupled
>> with vigorous exercise, kept him drug free and enabled him to avoid
> the
>> risks of CoQ10 depletion.
>>
>> The average healthy body has stored approximately 2,000 mg of CoQ10.
>> Each adult uses about 500 mg a day. The average diet provides 5 mg
>> daily. Where does the rest come from? We make it ourselves.
>>
>> Our body synthesizes CoQ10. If there is not enough, supplements can
>> bring up the slack. Internal synthesis of CoQ10 takes place in the
>> liver, peaking at about age 21-- and by 30, the rate begins to
> decline.
>> The process is similar to how the liver manufactures cholesterol.
> When
>> a statin reduces cholesterol production, it also restricts production
>> of CoQ10.
>>
>> Most of the 67 million people that orthodox medicine estimates are in
>> need of lifelong statin therapy are over age 50. Many were at risk
> for
>> CoQ10 deficiency even before they started on the drug. The statins
>> increase the prospect of harm. Last summer, the "Archives of
> Neurology"
>> published a study from Columbia University College of Physicians &
>> Surgeons reporting patients on Lipitor for 30 days had a 50 percent
>> fall in CoQ10 blood plasma levels.
>>
>> The drug company studies claim the risk is low, between .5 and 2.3
>> percent, depending on dose. That is somewhere between 335,000 and
>> 1,540,000 people experiencing adverse events. Given that the drug
>> companies only select healthy people for their drug studies, it is
>> highly unlikely any of them were taking other drugs known to deplete
>> CoQ10. The risk of serious adverse effects is almost certainly
> grossly
>> understated.
>>
>> When assessing the risks of statins, the cumulative effect of all
> drugs
>> prescribed for the patient must be the focus of attention. It rarely
>> is.
>>
>> Heart disease is an especially serious problem for patients with Type
>> II diabetes. Common drugs for diabetics that deplete CoQ10 include
>> Dymelor, Micronase and Tolinase. Another commonly prescribed diabetic
>> drug, Glucophage, depletes not only CoQ10, but also vitamin B12, a
>> second risk factor for heart disease.
>>
>> The cumulative effect of these diabetic drugs recently became a
> matter
>> for more concern. Last summer, in the "Annals of Internal Medicine,"
> a
>> prestigious journal with approximately 115,000 subscribers, it was
>> recommended that virtually all diabetics over 45 be prescribed a
>> lifetime regimen of statin drugs. Should we be surprised if
> diabetics'
>> rates of heart disease grow ever greater?
>>
>> People who are depressed may also be prescribed statins. Several
> drugs
>> commonly prescribed for depression deplete CoQ10: Adapin, Aventyl,
>> Elavil, Tofranil, Pamelor, Sinequan and Norpramin. Another reader,
>> suffering from neuropathy, was prescribed Elavil and two other pain
>> killers that deplete B12. Her doctor mentioned neither CoQ10 nor B12.
>> Yet these nutritional deficiencies are risk factors for the very
>> disease he was treating.
>>
>> Patients that are claimed to be at high risk because of elevated
>> cholesterol may also be taking other drugs targeting cardiovascular
>> disease. The following heart disease drugs may provide benefits, but
>> they may also have adverse effects on heart health. When combined
> with
>> statins, the total CoQ10 depletion could shift the balance from a net
>> benefit to an unacceptable risk. Those drugs include: Corgard,
> Inderal,
>> Lopressor, Betapac, Tenormin, Sectral, Biocardren, Aldomet, Catapres
>> and Apresoline.
>>
>> Orthodox medicine seems to have turned a blind eye to risks brought
> on
>> by nutrient depletion. Drug companies do not test for or report on
> its
>> consequences. The National Institutes of Health appears to be doing
>> little. The FDA is oblivious. It has been petitioned twice to require
> a
>> CoQ10 depletion warning for statins. So far, nothing.
>>
>> Of the near-dozen statin takers who wrote in response to last week's
>> column, only one reported being advised to supplement with CoQ10.
> More
>> broadly, last summer's Clinical Practice Guidelines for diabetics
> from
>> the American College of Physicians make no mention of CoQ10
>> supplements.
>>
>> What to do? When prescribed a drug, always ask your doctor if it
>> depletes any nutrients and, if so, what are the long term
> consequences.
>> Certainly, if prescribed a statin, ask, "Is CoQ10 right for me?"
>>
>> If you draw a blank with the doctor, try your pharmacist.
>>
>> Author and lawyer, Ken Baker is currently writing a book on
>> 20th-century psychiatry.
>>
>> http://www.rxpgnews.com/printer_297.shtml
>>
>> E-mail Ken Baker at kenbaker@andso.com.
>> By KEN BAKER
>>
>> New Perspectives Columnist
>
- Next message: Sharon Hope: "Researchers find Diabetes trigger, implications in heart disease"
- Previous message: Sharon Hope: "Re: More statin adverse effects to become obvious?"
- In reply to: Zee: "Re: drugs that deplete coq10"
- Next in thread: adam_becker_sr_at_yahoo.com: "Re: drugs that deplete coq10"
- Messages sorted by: [ date ] [ thread ]
Relevant Pages
|