Niacin heptatoxicity



Can anybody explain to me what this means. I read it in J Fam Pract. 2005
Mar;54(3):265-8.

Because [sustained-release/long-acting] niacin has an active metabolite
(nicotinamide), hepatotoxicity is more likely to occur with the
[sustained-release/long-acting] formulation than with [immediate-release]
niacin.

The article references Clin Liver Dis. 2003 May;7(2):415-33 but I dont have
this journal in my library.

Thanks

Robin


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