Re: Niacin + other B vitamins?

It seems to me I heard somewhere that Jim Heckman wrote in article
<11aq85vkpb3fs78@xxxxxxxxxxxxxxxxxx>:

>I have CAD and, in the wake an angioplasty, I've been taking high-dose
>(1000 mg) niacin + 40mg lovastatin, in the form of Advicor, to control
>my cholesterol. It works great, but I've been reading that one
>shouldn't supplement just one B vitamin without supplementing them
>all -- something about megadoses of one "crowding out" the others.

>Has anyone heard of this? I'm thinking of adding a so-called "Balanced
>B-100" vitamin formulation, which has thiamine, riboflavin, B-6, B-12
>and pantothenic acid at about the same doses, relative to their RDAs,
>as Advicor does niacin. But might this reduce the efficacy of the
>niacin by, say, competing with it in the gut and/or liver?

Just one data point: my first cardiologist (excellent man) started me
with 1000mg of Niacin, and I stayed at that level for about five years
with no suggestion about other B-complex items. About two years ago my
initial cardiologist reduced my dose to 500mb because he considered that
my numbers were suitable and stable, and still no other B-complex
medications.
--
Don Kirkman
.

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