Re: Progress in prevention of heart disease from inflammatory pathways and genes


"Jason" <jason@xxxxxxxxxx> wrote in message
news:jason-1606051255260001@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
> In article <24KdnR3HrPCKXizfRVn-sg@xxxxxxx>, "Robert"
> <Robertitsme@xxxxxxxxxxx> wrote:
>
> > "Jim Chinnis" <jchinnis@xxxxxxxxxxxxxxxx> wrote in message
> > news:p5a3b15pmpqkio0kakv8bk0v5o5vn8797j@xxxxxxxxxx
> > > This is very technical and hard going for those without a lot of
> > > biochemistry (including me), but it looks very promising. Maybe
> > > I'll drop my arachidonic acid and n-3 pufa intake even more...
> > >
> > > JAMA. 2005 May 11;293(18):2245-56.
> > >
> > > Effects of a 5-lipoxygenase-activating protein inhibitor on
> > > biomarkers associated with risk of myocardial infarction: a
> > > randomized trial.
> > >
> >
> > Cycloxygenase and lipoxygenase can have opposite effects depending on
the
> > tissue. In platelets cycloxygenase inhibition can decrease platelet
> > aggregation and make them less sticky. With the endothelial cells
inhibition
> > of lipoxygenase can inhibit the production of the prostaglandin
responsible
> > on making the cell less sticky or attachment by platelets and thus make
> > platelets stick.
> > Risk of MI with NSIAD etc.
>
> Robert,
> As you know--I'm not in the medical profession so don't really understand
> some of the medical terminology used in this report and various other
> research studies. Are there any new medications that treat blood pressure
> problems and cholesterol related problems?
Don't know what you mean by blood pressure and cholesterol related problems.
Look up metabolic sydrome or syndrome X for a clinical relationship.
As far as CAD the high blood pressure accellerates blood vessel disease via
hypercholesterolemia. High blood pressure is a clinical risk factor for
heart disease.

I probably have what is known
> as "familial hypercholesterolemia". I heard one person refer to it as "bad
> genes".
> Thanks in advance,
> Jason

Every disease is related to bad genes. All disease is an expression of
genetics, environmental precipitating factors.
I recommend the VAP lipid panel that goes beyond the typical lipid panel and
looks at particles size which is determined by genetics.
You can't change your genes but you can modulate the disease expression to a
certain extent in some cases by medication or diet or avoidance of
precipitating factors.

>
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.

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