Re: Statin-associated Muscle Problems
- From: "Bill" <xxx@xxxxx>
- Date: Sun, 19 Jun 2005 08:51:10 GMT
"Jason" <jason@xxxxxxxxxx> wrote in message
news:jason-1806051906370001@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>
>> So a 1 in a million chance according to this article, your muscle pains are
>> gone, you have not told her about the red rice, and you have
> discontinued the
>> statin. I would not see a need for such a test if I were her either.
>> However,
>> you can pay for it yourself. Also, you must also balance the risk of
>> statins
>> with the risk of not taking them.
>
>
> Hello,
> Thanks for your concern.
My concern is mostly about the way you are thinking about your problems. Not
that you have an underlying problem itself.
> Yes, most (but not all) of my muscle pains are
> gone. I am not a math expert but I have concluded that I was taking what
> is considered to be a very safe dose of statins. Provachol (Pravastatin)
> comes from the factory in 4 dose levels. I was taking the 20 mg dose. They
> also make a 10mg dose, 40 mg dose and a 80 mg dose. According to page 42
> of "What You Must Know About Statin Drugs..." by Jay S. Cohen, M.D., the
> actual "Manufacturer's recommended dose" is the 40 mg dose or the 80 mg
> dose. In other words, I am fairly certain that I was taking the equivalent
> of the 40 mg dose.
How do you know that?
>Therefore, it was a safe dose and should not have
> caused me to have muscle pains. I have not yet given up on statin use. Dr.
> Cohen mentioned on pages 154 and 160 of his book that some doctors tell
> their patients to use a pill splitter to cut [10 mg] pills in half.
> Perhaps if I took a 5 mg dose of Provachol each day--that it would not
> cause me to have muscle pain. What do you think about this idea? I should
> note that my total chol. level (169 MG/DL) during my last blood test was
> within normal limits. Dr. Cohen writes in his book that low doses of
> statins are less likely to cause side effects than medium and high doses.
>
> You mentioned that you would NOT have arranged for me to have a CK test if
> I told you that I had statin-associated muscle pain (myopathy).
That is not what I said at all. You said you had already stopped the statin
and that your next appointment was a month away.You had said some time ago
that your muscle pain was almost gone. With the statins stopped a while ago
and things improving greatly it would not seem the test is needed.
Bill
>The
> current procedures as per PMID: 11758079 are:
> "...Statin therapy should be stopped in cases of suspected myopathy, and
> serum creatine kinese levels should be checked and monitored". This same
> policy is discussed in the August 7, 2002 issue of the "Journal of the
> American College of Cardiology".
> I still believe that she should have done a CK test and told me to stop
> taking statin pills until after she seen the results of the CK test. She
> failed to follow the procedures mentioned above. You probably know that
> some cases of myopathy lead to rhabdomyolysis and various kidney
> disorders.
>
> Thanks again for your concern,
> Jason
>
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