Re: statins don't reduce dementia risk


"Bill" <xxx@xxxxx> wrote in message
news:bTgCe.2649$dX5.883@xxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>
> "Sharon Hope" <shope@xxxxxxxx> wrote in message
> news:FO-dnd2As82HrETfRVn-ig@xxxxxxxxxxxxxx
>>
>> "Bill" <xxx@xxxxx> wrote in message
>> news:G72Ce.2864$8y1.1260@xxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>>>
>>> "Sharon Hope" <shope@xxxxxxxx> wrote in message
>>> news:CMydnZtpKc2_CkXfRVn-gw@xxxxxxxxxxxxxx
>>>>
>>>> <tonywesley@xxxxxxxxx> wrote in message
>>>> news:1121407960.321980.4990@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>>>>> Jim Chinnis wrote:
>>>>>> tonywesley@xxxxxxxxx wrote in part:
>>>>>>
>>>>>> >zee wrote:
>>>>>> >> http://www.psycport.com/showArticle.cfm?xmlFile=usatoday_2005_07_12_eng-usatoday_life_eng-usatoday_life_021529_7391647621957932886.ew.xml&provider=USA%20TODAY
>>>>>> >>
>>>>>> >> "To get more proof, researchers will have to give a large number
>>>>>> >> of
>>>>>> >> middle-aged people either statins or placebo pills and then check
>>>>>> >> to
>>>>>> >> see whether the people getting the statins are shielded from the
>>>>>> >> disease years later."
>>>>>> >>
>>>>>> >>
>>>>>> >> <<speechless>>
>>>>>
>>>>>> >Another quote from that URL:
>>>>>> >
>>>>>> >"Participants took cognitive and memory tests throughout the study.
>>>>>> >The
>>>>>> >researchers found that those who took statins developed dementia or
>>>>>> >Alzheimer's at about the same rate as those who were not taking the
>>>>>> >drugs."
>>>>>
>>>>>> Yeah, but the difficulty is that you don't know how many of the
>>>>>> statin consumers would have developed dementia if they HADN'T
>>>>>> taken the statin. It's anybody's guess.
>>>>>
>>>>> Well, one could contend that it would be at the same rate at those who
>>>>> never took statins. But until we do the randomized double-blind
>>>>> tests,
>>>>> we won't know.
>>>>
>>>> However, don't count out the fact that the dementia caused by statin
>>>> adverse effects is able to be diagnosed in a way that rules out
>>>> Alzheimers, for example.
>>>>
>>>> So, the number of people who would have developed Alzheimers anyway is
>>>> no more pertinent than the number of people who would have developed
>>>> any other unrelated condition.
>>>>
>>>> For those dementias like Picks, which can only be diagnosed by biopsy
>>>> or autopsy, there is still a differential diagnosis possible, because
>>>> people who halt the statins and recover (even a little bit) would not
>>>> be recovering had the dementia been Picks.
>>>>
>>>> This is a dementia caused by statins. That it exists and can be
>>>> diagnosed via differential diagnosis is in and of itself a proof of
>>>> existence.
>>>
>>> Could you provide a reference for that. Thanks.
>>
>
> Is there an article on that.?
>
>> My husband's case is the prime example in my life. Alzheimer's, tau, and
>> other dementias were ruled out. Differential diagnosis makes it the
>> statin. Further, the s...l...o.....w recovery upon halting of statin,
>> even though it is not complete, is further evidence that the various
>> degenerative dementias are not in play - because they are degenerative.
>>
>
> Out of interest, how would you characterisze the recovery today. 10%, 50%,
> 90%?

Still waiting for test results....

impatiently

>
> Bill
>> Many many specialist exams and tests, and continuing monitoring and
>> testing clearly demonstrate this.
>>
>> I know of others who have experienced the same statin-caused dementia
>> adverse effects sequence.
>>
>> There is a difference.
>>
>> What is similar, however, is the effect on the quality of life of the
>> individual experiencing memory loss, confusion, amnesia, "big ragged
>> black holes" in memory.
>>
>> On any given day, a person who has active statin-caused dementia has to
>> deal with this has the same functional and emotional impact from the
>> memory loss as someone with Alzheimer's regardless of cause.
>>
>> However, in the longer term, the major difference is that those with the
>> degenerative diseases that cause dementia continue to decline. So
>> although their symptoms are similar to the statin-caused dementia adverse
>> effects, there is no known way proven to halt the progression (yet).
>> With the statin-caused dementia adverse effects, there is recovery
>> possible up to 80% of the original pre-statin cognitive abilities, per
>> Dr. Golomb's research presented at the International Coenzyme Q10
>> Association conference this year.
>>
>> In no way am I trying to minimize the emotional impact on the families of
>> the Alz patient, as they know it is fatal.
>>
>> However, the families of patients suffering dementia from statin adverse
>> effects, are affected by uncertainties and outrage, knowing it SHOULD
>> HAVE BEEN PREVENTED, and that there is no treatment, and that the net
>> effects are just as disabling and hurtful as Alz, and there is no
>> reliable prognosis, is also extremely difficult. Yes, we do rejoice that
>> it is not fatal, and after years of waiting we rejoice in the smallest of
>> improvements, but it is still a very difficult time.
>>
>>>
>>> Bill
>>>
>>>> If it is a demential unique to statin adverse effects, you would expect
>>>> none of the non-statin-taking population (and non-red yeast rice-taking
>>>> population) to develop that particular type of dementia, and other
>>>> types would be unrelated (except, perhaps, as an indicator of who might
>>>> be predisposed to a dementia expression).
>>>>
>>>> Certainly, if you could identify a naturally occurring dementia that
>>>> was comparable, then the 'gold standard' would apply, but so far that
>>>> hasn't been the case with statin dementia.
>>>>
>>>> Typically, with the more extreme statin adverse effects, only
>>>> pediatricians are familiar with the constellation of symptoms, because
>>>> only infants having some extreme congenital lipid processing defect, or
>>>> mitochondrial defect or CoQ10 deficiency exhibit them. These infants
>>>> either have the condition corrected, or they do not become adults.
>>>> Thus, adult doctors are at such a loss when presented by these 'rare'
>>>> constellations of symptoms.
>>>>
>>>>>
>>>>> Looking at the abstract
>>>>> http://archneur.ama-assn.org/cgi/content/short/62/7/1047
>>>>> I found this interesting:
>>>>> "... in secondary analyses, current use of statins compared with
>>>>> nonuse of LLAs was associated with HRs of 0.69 (95% CI, 0.46-1.02) for
>>>>> all-cause dementia and 0.56 (95% CI, 0.35-0.92) for any Alzheimer
>>>>> disease."
>>>>>
>>>>
>>>>
>>>
>>>
>>
>>
>
>


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Relevant Pages

  • Re: statins dont reduce dementia risk
    ... a person who has active statin-caused dementia has to deal ... > with this has the same functional and emotional impact from the memory loss ... > statin-caused dementia adverse effects, there is recovery possible up to 80% ... > after years of waiting we rejoice in the smallest of improvements, ...
    (sci.med.cardiology)
  • Re: statins dont reduce dementia risk
    ... >> holes" in memory. ... >> their symptoms are similar to the statin-caused dementia adverse effects, ... >> after years of waiting we rejoice in the smallest of improvements, ...
    (sci.med.cardiology)
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