Re: did statin drug cause this amnesia
- From: <Hawki63@xxxxxxxxxxxxx>
- Date: Wed, 20 Jul 2005 17:18:04 GMT
"Jason" <jason@xxxxxxxxxx> wrote in message
news:jason-2007050857510001@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
> In article <mUmDe.1196$Fk4.916@xxxxxxxxxxxxxxxxxxxxxxxxxx>,
> <Hawki63@xxxxxxxxxxxxx> wrote:
>
>> "Sharon Hope" <shope@xxxxxxxx> wrote in message
>> news:MYmdnT3IDudCEkDfRVn-tQ@xxxxxxxxxxxxxx
>> >
>> > <Hawki63@xxxxxxxxxxxxx> wrote in message
>> > news:Am1De.8118$NU2.1426@xxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>> >>
>> >> "Sharon Hope" <shope@xxxxxxxx> wrote in message
>> >> news:2qWdnQw87aOHA0HfRVn-jw@xxxxxxxxxxxxxx
>> >>> For anyone who has any question at all about what kinds of
>> >>> experiences
>> >>> are common among those who experience this known statin adverse
>> >>> effect,
>> >>> Dr. Graveline has just written a new book, following "Lipitor, Thief
>> >>> of
>> >>> Memory," and it is excellent.
>> >>>
>> >>> "Statin Drug Side Effects:
>> >>> the misguided war on cholesterol"is now available
>> >>> at this link:
>> >>> http://www.firmprice.com/spacedoc/
>> >>>
>> >>> Dr. Graveline has impeccable credentials. He has been a NASA Science
>> >>> Astronaut, a USAF Flight Surgeon, a family doctor, and an author.
>> >>> He,
>> >>> himself, suffered more than one episode of transient global amnesia
>> >>> as
>> >>> an adverse effect of Lipitor.
>> >>>
>> >>>
>> >>> Statin drugs, including Atorvastatin (aka Lipitor), fluvastatin (aka
>> >>> Lescol), lovastatin (aka Mevacor), pravastatin (aka Pravachol),
>> >>> simvastatin (aka Zocor), rosuvastatin (aka Crestor), and cerivastatin
>> >>> (Baycol), are known to cause transient global amnesia.
>> >>>
>> >>> Pfizer lists "amnesia" on the label for Lipitor.
>> >>>
>> >>> Amnesia is one of the many types of cognitive damage caused by
>> >>> statins.
>> >>>
>> >>>
>> >>> "zee" <outrider@xxxxxxxxxxxxx> wrote in message
>> >>> news:1121726419.597869.231270@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>> >>>> Posted on Mon, Jul. 18, 2005
>> >>>>
>> >>>>
> http://www.charlotte.com/mld/charlotte/living/health/12158484.htm?source=rss&channel=charlotte_health
>> >>>>
>> >>>> PEOPLE'S PHARMACY | JOE GRAEDON AND TERESA GRAEDON
>> >>>>
>> >>>> Did statin drug cause amnesia?
>> >>>>
>> >>>> My cholesterol has always been around 200, but I have a bad family
>> >>>> history and a past angioplasty. In addition to a good diet and
>> >>>> regular
>> >>>> exercise, my doctor has prescribed various statin drugs to lower my
>> >>>> cholesterol. Three different ones have given me peripheral
>> >>>> neuropathy
>> >>>> (pins and needles). On Niaspan and Zetia my total cholesterol is
>> >>>> 160,
>> >>>> with bad LDL at 97. My doctor wants it below 80 so he prescribed
>> >>>> Crestor, which he takes himself. I started on Friday, and on Sunday
>> >>>> I
>> >>>> woke with what has been diagnosed as transient global amnesia. I
>> >>>> played
>> >>>> golf that morning and played well, but I kept asking the same
>> >>>> questions
>> >>>> over and over. My wife and my golfing partners decided I should go
>> >>>> to
>> >>>> the hospital after nine holes. This began at 7 a.m., and I did not
>> >>>> regain any short-term memory until 3 p.m. By 5 p.m. I was back to
>> >>>> normal. The doctors doubt the Crestor was responsible. Could it have
>> >>>> been?
>> >>>>
>> >>>> We can't say whether Crestor caused your transient global amnesia
>> >>>> (TGA), but others have reported memory problems and TGA while taking
>> >>>> statin cholesterol-lowering medicines. The first person we heard
>> >>>> from
>> >>>> was Dr. Duane Graveline. He described his experience in the book
>> >>>> "Lipitor: Thief of Memory."
>> >>>>
>> >>>> TGA is not a common side effect, but it is very distressing. You and
>> >>>> your doctor may need to find something other than a statin to reduce
>> >>>> your LDL cholesterol further.
>> >>>>
>> >>>>
>> >>>> fairuse
>> >>>>
>> >>>
>> >>
>> >>
>> >> Sharon..
>> >>
>> >> I don't think anyone has ever doubted that these AE can and do
>> >> occur.....and that continuing to study etc is important
>> >>
>> >> unfortunately..there are very few..maybe NO drugs that don't affect
>> >> some
>> >> adversely...
>> >>
>> >> I wish there was a way to predict responses...
>> >>
>> >>
>> >
>> > One way is for the studies for approval to collect AEs,
>> > another is to be open and above board about AEs,
>> > another is mandatory reporting of all AEs (recognized) and mandatory
>> > reporting of all unexplained symptoms including all drugs used by the
>> > patient.
>> >
>> > Web-based reporting can make these anonymized reports from doctors and
>> > clinics quick and efficient, and computer analysis can find patterns.
>> >
>> > The next step would be genetic analysis for those who suffer serious
>> > adverse effects. This needs to be done at least in the first 7 years
>> > of a
>> > newly approved drug, and extended anytime its target audience is
>> > enlarged.
>> >
>> > The cost of tracking the AEs should be shared by the approving
>> > authority
>> > (i.e., FDA public funds) and the drug company, as a cost of doing
>> > business. This would include, for serious AEs, the cost of running the
>> > genetic tests (maintaining patient anonynimity, tracking only to the
>> > doctor or clinic).
>> >
>> > Not everything would be genetic, so other avenues would also need to be
>> > explored, but the endpoint is determining whom to screen out. And
>> > warnings and pre-testing would need to then be implemented prior to new
>> > prescriptions. At that point, where it becomes preventative for
>> > individual patient care, the patient or his insurance would need to
>> > shoulder the cost. This scheme offers a bit of an edge to new
>> > medications,
>> > in that the patients who experience early side-effects are somewhat
>> > protected from the costs (but still, suffer serious side effects),
>> > thereby
>> > making some less reluctant to try the newest drug on the market.
>> >
>> > The next step would be to find a treatment to a cure for those who
>> > still
>> > have the serious adverse effects. They should not be forgotten.
>> >
>> > Then, too, the results of all of this must get folded back into the
>> > risk
>> > analysis cost /benefit (cost= human pain & suffering) tradeoffs, so
>> > that
>> > the approval process for new drugs is improved in real-time with every
>> > new
>> > piece of data.
>> >
>> > Not free, but the cost of drug side effects is very high now, just not
>> > tracked well. Don't forget that statistic (which DID NOT COUNT THE
>> > COST
>> > OF INSURANCE) that ~50% of all bankruptcies are for Medical Costs over
>> > and
>> > above what insurance pays for in families who have medical insurance.
>>
>> this has always surprised...if not ..confused me....
>>
>> I suppose we have always had excellent insurance (since retirement paying
>> for coverage...premiums of $20,000 per year...til Medicare at age
>> 65)....our
>> "out of pocket and share of costs" have always had a maximum....current
>> plan
>> ..for me....is $250 deductible,,$1000 max co insurance..plus $10 and $20
>> copays for scripts...
>>
>> how could/would anyone with insurance go bankrupt?? unless they didn't
>> have
>> about $3000 a year (using above figures)..
>>
>> in other words..if I needed a liver transplant next week...my out of
>> would not be higher than the above example...except for more meds...??
>>
>> am I missing something??
>>
>> I thought the bankruptcy thing was for the UNinsured..or maybe the
>> underinsured??
>>
>> do you have a reference??
>>
>
> Hawki,
> I have a neighbor that is about 45 years old. He had a full time job and
> everything was going great in his life.
except he forgot to save for a rainy day
He was involved in a car accident
> and his back was injured. The insurance covered all of his medical costs.
> However, he lost his job and is now on disability pay.
Social Security disability comes with Medicaid health coverage...has he
looked into that??
He no longer has an
> income from his job. He is now bankrupt. This sort of problem is much
> worse for people that don't have health insurance. In some cases, the
> insurance programs do not cover all of the expenses related to medical
> care.
no one implied they did....read the data on "medical
bankruptcies"....average amount of medical debt causing the bankruptcy was
quoted as $13,000......I realize for many that is a very high
figure...instead of declaring bankruptcy...one can begin paying it
off...even $20 a month will keep the bill collectors at bay
unfortunately far too many folks find it easier to throw up their hands ....
one cannot have a shitload of toys..and then admit that $13,000 throws them
into bankruptcy....
as for your friend...disability is a reality...depending upon where he
lives...states ALL have medical coverage for those in his predictment...
> Jason
>
> --
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- From: Sharon Hope
- Re: did statin drug cause this amnesia
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