Re: Controlling Hypertension: Medicine vs. Excercise


"Robert" <Robertitsme@xxxxxxxxxxx> wrote in message
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Lancet. 1998 Aug 1;352(9125):397-9. Related Articles, Books, LinkOut


Comment in:
Lancet. 1998 Nov 7;352(9139):1557-8.
Lancet. 2001 Feb 24;357(9256):639.
Lancet. 2001 Mar 24;357(9260):957.

Aetiology of transient global amnesia.

Lewis SL.

Department of Neurological Sciences, Rush-Presbyterian-St Luke's Medical
Center, Chicago, IL 60612, USA. slewis@xxxxxxxxxxxxxx

The pathophysiology of transient global amnesia (TGA) has been obscure since
the definition of this syndrome more than 30 years ago. Current hypotheses
include migraine, seizure, or transient cerebral arterial ischaemia.
However, none of these potential mechanisms explain both the absence of
other neurological signs or symptoms during TGA, and its frequent
precipitating activities: many of which would be expected to result in
marked increases in venous return from the arms to the superior vena cava.
Patients with TGA also commonly have a Valsalva manoeuvre at the onset of
attacks. I suggest that a Valsalva manoeuvre, blocking venous return through
the superior vena cava, may allow brief retrograde transmission of high
venous pressure from the arms to the cerebral venous system, resulting in
venous ischaemia to the diencephalon or mesial temporal lobes and to TGA.

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PMID: 9717945 [PubMed - indexed for MEDLINE]


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