Re: CABG Alzhelimer's Study


"Jim Chinnis" <jchinnis@xxxxxxxxxxxxxxxx> wrote in message
news:oiqsg15lm6fj1gnod8i3ive2auv9rla4b3@xxxxxxxxxx
> "jay1000" <jfschonSpamguarD@xxxxxxx> wrote in part:
>
>>Wolzen makes it sound like he is inventing the wheel. No one needs
>>confirmation of Alzeimers risk to do their best to protect the brain
>>during
>>CABG. The term "pumphead" has been long used to informally identify
>>patients
>>with cognitive problems following open heart surgery. For a while the
>>pump
>>was believed to be the culprit but it happens with beating heart CABG.
>
> Do you have a cite? Or the name of a researcher?
> --
> Jim Chinnis Warrenton, Virginia, USA


Jim,

I saved this article as a stripped htm file on my local drive. You would
have to do a search to find the cite. Don't even know what edition of Stoke
it came from. But it was pre-1998 when I was delving into brain damage.
Don't have much else saved. I did remember microemboli!!!

Also recall that off-pump reduced the incidence of memory problems.

Rewarming rate affected the incidence of memory problems

Immune response entered into it.

And, of course, surgical skill. Precise location of the bypass tube (forgot
what they call it) is super-important because the installation of the tube
can break off brittle plaque (emboli).

NY & NJ rate cardiac surgeons based on RISK ADJUSTED mortality and there is
a 400% difference between the best and the worst. Presumably the best for
mortality would also be best for neurological problems.

Jay


Fat Particles Released During Heart Surgery Can Damage Brain

--------------------------------------------------------------------------------

--------------------------------------------------------------------------------

WINSTON-SALEM, N.C. -- The longer heart surgery takes, the more tiny
particles of fat enter the bloodstream and circulate to the brain, blocking
tiny blood vessels, Wake Forest University researchers reported in the March
issue of Stroke, an American Heart Association journal.

The number of fat particles, called microemboli, increase dramatically the
longer a patient remains on the heart-lung machine, which temporarily does
the work of the heart and lungs during surgery. By blocking the tiny blood
vessels, the microemboli can cause brain deficits that may be permanent in
ten to thirty percent of affected patients. For each hour spent on the
heart-lung machine, the number of emboli increased by 90.5 percent, reported
William R. Brown, Ph.D., Dixon M. Moody, M.D. and other researchers.


The heart-lung machine -- known as cardiopulmonary bypass -- is most
commonly used in coronary artery bypass grafting, done in 598,000 patients
in 1996, according to the Heart Association. Other forms of heart surgery --
such as heart valve replacement -- also use cardiopulmonary bypass.


"Current estimates indicate that more than 50 percent of patients who
undergo cardiopulmonary bypass have neurologic or neuropsychological
deficits during the first week after surgery," Brown, Moody and their
colleagues said. "Ten to thirty percent have long-term or permanent deficits
and 1 to 5 percent suffer severe disability or death." They said microemboli
"have long been a suspected cause" of memory loss and other brain problems
following cardiopulmonary bypass......



.

Relevant Pages

  • ~*Online WACOC News 2006 June 26*~
    ... Fibromyalgia pain isn't all in the patients' heads, new brain study ...
    (alt.med.fibromyalgia)
  • Harnessing Thought to Help the Injured
    ... Scientists have long dreamed of harnessing thoughts to allow amputees ... Results released today from a clinical trial of four paralyzed patients ... Nature that a patient who had electrodes implanted in his brain used ... The study was paid for and the brain implant built by Cyberkinetics ...
    (alt.support.mult-sclerosis)
  • Re: OT; latest tinfoil beanie technology
    ... Wow...Michigan is just loaded with agents that are married to other ... FDA already APPROVED verichip to be IMPLANTED in patients bodies. ... electrodes implanted in his brain used his thoughts to control a computer ... paid for and the brain implant built by Cyberkinetics Neurotechnology ...
    (alt.security.alarms)
  • Re: OT; latest tinfoil beanie technology
    ... www.infospace.com under their UNDERCOVER AGENTS HUSBANDS names Larry Wahl ... FDA already APPROVED verichip to be IMPLANTED in patients bodies. ... electrodes implanted in his brain used his thoughts to control a computer ... paid for and the brain implant built by Cyberkinetics Neurotechnology ...
    (alt.security.alarms)
  • Re: the liver and the brain
    ... I thought it might be useful to contrast the brain with the ... > The human heart was long regarded as the seat of all sorts of mystical ... > that it is, in fact, a pump. ...
    (sci.cognitive)