Re: Possible problem lowering triglycierides too much with Lipitor???



In article <Xns96E6A612710BCsome1outthere@xxxxxxxxxxxxx>, listener
<listener@xxxxxxxxxx> wrote:

> jason@xxxxxxxxxx (Jason) wrote in
> news:jason-0510051241560001@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx:
>
> > In article <hOCdndzsZtWqiNneRVn-iA@xxxxxxx>, "Robert"
> > <RobertsSong@xxxxxxxxxxx> wrote:
> >
> >> "Flycaster" <adam999forgetit@xxxxxxxxxxxx> wrote in message
> >> news:2uOdnV88rZTQNt7eRVn-hQ@xxxxxxxxxxxxxxx
> >> > I'm 66 yo, 6' tall and weigh 164, play 1.5-3 hours tennis (doubles
> >> > at 3.5 level) 5-7 days/wk, lift weights every other day for 1 hour,
> >> > with an overall muscular and slender build and have always been
> >> > active and in good shape and good health. My mother also was in
> >> > great shape and active, but with high cholesterol (controlled by
> >> > diet and statin), when she suddenly died at 83 (no documented
> >> > cause) while in apparently good health. My last two cholesterol
> >> > tests (9/03 and 2/05) gave the following values respectively:
> >> >
> >> > Total: 205 220
> >> > HDL: 56 65
> >> > LDL: 139 139
> >> > Ratio: 3.7 3.4
> >> > Trigly: 52 82
> >> >
> >> > Although my cholesterol levels have always been in the 200-230
> >> > range, none of my internists have opted for me to go on statins.
> >> > They have said that my "fat" profiles looked good and precluded the
> >> > use of statins. However, reading about the overall value of
> >> > statins (I was in the pharmaceutical industry for 32 years and know
> >> > something about how to evaluate medical research) and their
> >> > potential for cardio-protectiveness,
> >>
> >> Statins reduce lipids and therefore antiarthrogenic and are
> >> cardio-protective during AMI.
> >> At your age I would take fish oils for cardio protection.
> >> Depending on the individual they may be hard to tolerate. I have
> >> always had GI problems before statins and they certainly don't help
> >> me with that.
> >
> > Robert,
> > Another great post. I hope that Sharon responds to the OP. I seem to
> > recall a study mentioned in her report that stated that elderly people
> > have more serious side effects when they take statins. I don't recall
> > the reason. I just checked Dr. Cohen's book and he has a section on
> > page 76-78 labelled "Seniors and Statins". The first sentence in that
> > section states: "Side effects hit seniors the hardest...the overall
> > incidents of adverse drug reactions in the elderly is two to three
> > times that found in young adults."
> > Jason
> >
>
> Can you tell me specifically what studies Cohen relies on to make that
> statement? I'd like to read them.
>
> Thanks.
>
> L.

L.,
Yes--here's the source:
Montamat, S.C., Cusack, B.J., Vestal, R.E. "Management of drug therapy in
the elderly." The New England Journal of Medicine 1989: 321 (5) 303-309.
Jason

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