Re: Statins may delay effects of Alzheimer's: study
- From: "Sharon Hope" <shope@xxxxxxxx>
- Date: Sun, 20 Nov 2005 11:59:18 -0800
That is a slightly different test. Yours is, of course, is logical and
straightforward, and what the actual results might show.
However, the statin companies' marketing hype and spin claims that statins
affect the progression of Alzheimer's DISEASE, not quite the same as harmful
to the population.
My concern is that there is currently no study that uses a test to
distinguish the difference between cognitive damage due to statins and
cognitive damage due to Alzheimer's Disease. Since it is clearly documented
that both have negative cognitive effects, unless and until the damage can
be differentiated by cause, the results of such studies cannot claim to
indicate the influence on the progression of Alzheimer's DISEASE.
And that is exactly what they claim.
"David Rind" <drind@xxxxxxxxxxxxxxxxxxxxx> wrote in message
news:dlm59v$n4q$1@xxxxxxxxxxxxxxxxxxxx
> Sharon Hope wrote:
>> For it to really be straightforward, they would need to develop a
>> credible test to distinguish the difference between memory loss due to
>> Alzheimer's and memory loss caused by statins among the study
>> participants.
>>
>> Without that, no such study has much credibility or practical use.
>
> No they wouldn't.
>
> If you take a bunch of people with early Alzheimer's and randomly give
> them a statin or placebo, three things can happen:
>
> 1) There may be no difference in memory loss between the two groups
> (statins had no effect on memory loss in this population)
> 2) There may be decreased memory loss in the people who got statins
> (statins were protective in this population)
> 3) There may be increased memory loss in the people who got statins
> (statins were harmful in this population)
>
> Notice that we did not need a memory test that could distinguish what was
> causing the memory loss -- the study itself was able to tell us whether,
> on balance, statins had more beneficial or more harmful effects on memory
> in people with early Alzheimer's.
>
> --
> David Rind
> drind@xxxxxxxxxxxxxxxxxxxxx
>
.
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