Re: Outcomes in 45 patients with statin-associated myopathy
- From: "Sharon Hope" <shope@xxxxxxxx>
- Date: Wed, 21 Dec 2005 20:08:30 -0800
"listener" <listener@xxxxxxxxxx> wrote in message
news:Xns97327B6471FB3some1outthere@xxxxxxxxxxxxxxxxx
> "Sharon Hope" <shope@xxxxxxxx> wrote in news:pN-
> dnT4oRZvCGjre4p2dnA@xxxxxxxxxxx:
>
>
>> "Robert" <Robertsononlin@xxxxxxxxxxx> wrote in message
>> news:OeCdnfP1MbEYpDvenZ2dnUVZ_t6dnZ2d@xxxxxxxxxx
>>> I am referring to diagnostic probability. Of 437 patients with
> possible
>>> statin muscle problems only 45 were proven.
>>
>
>
>> So what? That is more than 10%. For those 45 people, it does not
> matter
>> one whit how many others are suffering the same fate.
>>
>> Repeat: TEN PERCENT
>
> BUT!
> "Patients with statin-associated myopathy experienced full resolution of
> muscle pain on cessation of statin therapy."
>
So you think this makes them feel better that they experienced extreme
muscle damage and pain, to the degree that medical intervention was needed -
or it would never have shown up in the records search, but since there was
no permanent damage they were happy to have had their lives interrupted for
this PREVENTABLE experience? The pain does not count? The muscle weakness
does not count? Get real.
> AND!
> Of those patients 13% required hospitalization which translates to
> sightly over 1% of the entire group that suffered a severe AE.
>
What is your point. Are you defending AEs so drastic and life-threatening
as to require hospitalization?
> .....
>
>> For the others, it was not DIS-proven, it only meant that the doctors
> did
>> not keep records adequately enough to support the trial.
>
> WHA?
>
It was a RETROSPECTIVE study, looking through medical records. If a doctor
did not follow up on the patient's complaints of muscle pain and damage (and
AGAIN, it had to be serious enough to have made the medical record or it
would not have been part of the pool in the first place) by having more
tests run, the record did not qualify for the 10%.
That does NOT imply there was no damage, only that the doctor in question
did not follow up with further testing.
In every one of the pool of records, there was an entry in the medical
record that the patient had experienced muscle pain or muscle damage
subsequent to starting a statin. The patient had to have made enough of a
point of it that IT WAS WRITTEN IN THE MEDICAL RECORD.
> .....
>
>>
>> TEN PERCENT of these people suffered grave muscle damage - the kind of
>> damage that the ACC, AHA, and NIH NHLBI jointly warned about.
>
>
> Again, this is just not true. You are making an erroneous claim. Only
> slightly over 1% suffered severe enough AE that they had to be admitted
> for hospitalization AND, according to the study, there were no deaths AND
> hospitalized patients were more likely to be taking concomitant
> medications known to increase the risk of statin-associated myopathy
> apparently, AND even they "experienced full resolution of muscle pain on
> cessation of statin therapy."
>
> I see your m.o. is still about twisting, distorting, overreaching.
>
Twisting, distorting, and overreaching is what you have done in your
simplification and dismissal of people suffering PREVENTABLE damage.
Never have I heard a person who was mugged (beaten and robbed) say that it
was trivial because they were not hospitalized or dead. They were
TRAUMATIZED.
You remind me of the alcoholic who drives drunk, hits another car, watches
as the Jaws of Life are needed to extricate the person and all the while
scoffs dismissively, 'they weren't HURT - they didn't have to go to the
hospital and they aren't dead. No big deal.'
Same twisted, distorted perspective you habitually offer.
For those damaged by statins, and for those hit by drunk drivers or attacked
by muggers, it is A BIG DEAL, it is TRAUMATIC, it steals QUALITY OF LIFE.
Hospitalization and death are not only measures of unpleasantness.
> L.
> .
>
>
.
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