Re: Carbs and Cholesterol.

On Thu, 25 May 2006 17:30:15 +0300, Matti Narkia <mna@xxxxxxxx> wrote:

Also, as we know, alpha-linolenic acid has been associated with
increased risk of prostate cancer:

Brouwer IA, Katan MB, Zock PL.
Dietary alpha-linolenic acid is associated with reduced risk of fatal
coronary heart disease, but increased prostate cancer risk: a
meta-analysis.
J Nutr. 2004 Apr;134(4):919-22.
PMID: 15051847 [PubMed - indexed for MEDLINE]
<http://www.nutrition.org/cgi/content/full/134/4/919>

If both effects are real, the men have to decide, whether to try to
decrease the risk of sudden cardiac death or prostate cancer. The
latter would cause more suffering, so my bet is to try to reduce the
risk of prostate cancer, especially because fatty fish and fish oil
can be used instead of alpha-linolenic acid to help to prevent the
former. Taking some fish oil at every meal, which does not contain
fatty fish, could perhaps also prevent the blood vessel constriction
after meal. Has anyone tested this?

I didn't find exactly that kind of study, but these two studies found
tha fish oil inhibited vasconstriction in healthy subjects and
improved vasorelaxation in hypercholesterolemic patients.

Chin JP, Gust AP, Nestel PJ, Dart AM.
Marine oils dose-dependently inhibit vasoconstriction of forearm
resistance vessels in humans.
Hypertension. 1993 Jan;21(1):22-8.
PMID: 8418020 [PubMed - indexed for MEDLINE]
<http://hyper.ahajournals.org/cgi/content/abstract/21/1/22?>
<http://hyper.ahajournals.org/cgi/reprint/21/1/22> (full text PDF)

Goode GK, Garcia S, Heagerty AM.
Dietary supplementation with marine fish oil improves in vitro small
artery endothelial function in hypercholesterolemic patients: a
double-blind placebo-controlled study.
Circulation. 1997 Nov 4;96(9):2802-7.
PMID: 9386141 [PubMed - indexed for MEDLINE]
<http://circ.ahajournals.org/cgi/content/full/96/9/2802>


--
Matti Narkia
.

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