Re: Can altered vascular permeability effect glocose levels?
- From: "Kumar" <lordshiva5753@xxxxxxxxxxxxxx>
- Date: 27 May 2006 02:30:08 -0700
There are some intestinal secrations which can enhance more insulin
secrations. Whether E.Coli infection effect such effect of enhanced
insulin(may be more secration)?
"Local blood flow control can be divided into two phases;
1)Acute - rapid change constriction/dilatation of arteriols,
metarteriol et spincters.
2)Long-term control provides a better control by increasing/decreasing
the physical size and number of blood vessels supplying the tissues. "
Diabetic2 patients can have persistent hyperglycemia due to excess
craving and overeating. They can also opt for sed. lifestyle due to
predisposition or due to diabetic pathology.Consequently, supply of
glucose and nutrients can be more to tissues and demand/need of them
may be less. As such excess glucose, nutrients etc. may cause some
toxicity to target tissues. To save from this and in view of above, can
chronically elevated blood glucose levels and of other nutrients in
blood cause some morphological changes by decreasing the physical size
and number of blood vessels supplying the tissues as "long term blood
flow regulation", naturally?
How added insulin--medicated or injected, can behave in opposite to
above natural body's mechanism of restricting excess exposure of
nutrients to cells, in view of dilating effect mediated by added
insulin? Can such added insulin cause gluco/nutrient toxicity or excess
exposure to target cells?
Btw, whether such added insulin, is exposed to blood and target cells,
for prolonged time or for whole day (long acting) persistently ? If
yes, what can be its impact?
.
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