Re: Statins and muscle damage
- From: ritpg@xxxxxxxxxxx
- Date: 22 Jun 2006 13:15:52 -0700
David Rind wrote:
Jason Johnson wrote:
I done some research on this subject last year when I developed muscle
problems as a result of taking statins. I found out (at that time) that
checking the blood levels of creatine kinase (CK) was the best method
of finding out if a patient is experiencing muscle wasting or rhabdomyolysis.
There is no evidence that I know of that checking a CK tells anything at
all about "muscle wasting" in patients on statins. It's not even known
if statins cause "muscle wasting". Feel free to post a citation to a
primary study if you think otherwise.
CK is commonly elevated in people who have muscle symptoms (pain,
weakness, decreased exercise tolerance) on statins, but there is good
evidence that not everyone has an elevated CK even when a statin is
responsible for such symptoms.
As for rhabdomyolysis, a CK would certainly answer that question, but
rhabdo is a rare problem and is not asymptomatic. It has nothing to do
with the OP's question.
--
David Rind
drind@xxxxxxxxxxxxxxxxxxxxx
I have been having a problem with synthetic statins for about 8 years.
My somewhat unscientific observation is that there has been a direct
correlation between the dosage of sysnthetic statin I've taken, my CPK
level and my level of muscular discomfort. My doc has been doing
bloodwork on me at least every 6 months over this period. I personally
think, based on conversations with many people over the years, that
this relationship between synthetic statins and muscular discomfort,
and possibly wasting, is a much large problem than anyone knows or
wants to admit. It's been amazing to me to see how many people have
tended to attribute the pain to aging only to find out that there CPK
is elevated. Such attribution shouldn't surprise anyone because of the
fact that many if not most people taking the synthetic statins belong
to the age group that would tend to make such a connection. I may be
unique in that I've had this problem possibly as long as anyone I know.
I am becomong concerned about the possibility of muscle wasting. I've
noticed that my legs have become very thin compared to the rest of
structure. I've gotten used to the pain but loss of strength, which I
believe I am experiencing (or is it age?), can be even more
disconcerting. So who's going to pay for a proper study? Certainly
not the pharmaceutical companies who are making billions from the sale
of synthetic statins meds. The FDA? That organization has been
nothing short of a joke since the Clinton administration. I hate the
position I'm in: knowing that synthetic statin meds might be killing
me (after all, the heart is a muscle too, right?) while being told that
I have to keep my cholesterol down to the 150 range to survive. I pray
for the day when someone discovers an alternative to statin and I hope
it isn't too late for me.
.
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