Re: Lack of evidence for LDL treatment targets

x-no-archive: yes

James216440@xxxxxxxxx wrote:


I want to personally thank you for your above post. It is an
understandable post that gives great insight into when statins are
appropriate based on all kinds of available data.
Folks can argue all
they want about the funding source but the data is still data and those
of us who have been involved in developing regulatory data know such
data can not simply be ash canned because you do not like the results.

Grammatically speaking, "the data *are* the data." And lots of folks in the scientific community think we can't trust the data.

And it makes no difference if the results are favorable to the funder
or unfavorable. Once he has done the study he is stuck with the data
just like the rest of us are stuck with the data.

One who does studies too often exercises selection over what to include and what not to include as adverse reactions and as benefits.


I have said over and over that there exist classes of people who
benefit from statins. Not one of the pro statin people ever
acknowledges that I have ever said such things. I have also, like
Susan, said over and over there exist classes of people who have shown
no benefit from statin treatment that justifys the risk and expense.
That brings a storm of denial from the pro statin people and snarky
comments from some of the most ignorant. I have said repeatedly that
it is not a bit clear, based on the evidence, that those who benefit
get that benefit as a result of lower cholestorol. That is like
pouring gasoline on a fire. It is interesting that this is such a
black and white issue with such a large group of people on both sides.
I can only conclude talking about who benefits from statins and who
does not benefit is like talking religion or politics.

It's not quite that simple; whether or not there are truly benefits that outweigh the risks of ststins remains to be proven in truly independent, unbiased study with trustworthy data. Accepting data due to quantity is what bought women on HRT years of increased health risks that *everybody knew* were supposed to be reduced by HRT.

I think of statin research as analogous to the HRT decades. Unproven benefits, known risks.

I'm willing to be convinced when independent verification by sources who don't simply assume the earlier conclusions are all valid or truthful(as happened with HRT) show they exist.

Susan
.

Relevant Pages

  • Re: got my hospital records
    ... I'll see what my lipids look like in November. ... Whether a statin is needed to reduce the ... probability of another heart attack or a stroke is hard to say. ... You may be right this time, but you should be sure your risks are ...
    (alt.support.diabetes)
  • Re: Factors Associated with Findings of Published Trials of Drug-Drug Comparisons: Why Some Stat
    ... Bristol-Myers Squibb, the makers of pravastatin--not Pfizer, the makers of ... What are we to extrapolate from that, in a more general sense, about the overall reliability of statin studies? ... Any time the issue has been thoughtfully examined, financial stakes have played a role in under reporting risks and over reporting benefits. ... grain industry have everyone afraid of fats and meat and cheese and ... ...
    (sci.med.cardiology)
  • Re: Question about Red Yeast Rice
    ... >>> why in the world were you taking a statin at all, ... About two years ago, my total chol. ... > benefits of Ginko with no statements of risks. ... > into my query to come up with some that pointed out the risks. ...
    (sci.med.cardiology)
  • Re: Statins again.
    ... Statistical significance has ... occurred between placebo and statin groups are unlikely to be due to chance. ... you are like the people in the study (in terms of risks and response to ... That still doesn't mean you should take the drug. ...
    (sci.med.cardiology)
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