Re: problem with generic nifedipine


"William Wagner" <not-to-here-williamwag@xxxxxxxxx> wrote in message news:not-to-here-williamwag-C77CC5.09264128022007@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
In article <8_fFh.11253$tA1.1697@trndny02>,
"Jeff" <news@xxxxxxxxxxxxxx> wrote:

<theodoric3@xxxxxxxxx> wrote in message
news:1172665416.595457.186810@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
> BP was nicely under control, 130-75, using Adalat nifedipine 90mg.
> Switched to generic, Mylan labs 90mg and BP soared to 145-95, tested
> for a week. Placed a pill of each in water. After two hours the Adalat
> brand had softened and began to breakdown. The Myan pill lost it's
> cosmetic coating but was hard and and same size. Is anyone aware of
> this problem? Can the generic pill be cut in half safely to speed
> absorbtion?

Call your doctor. Your blood pressure could be high for other reasons. In
addition, your doctor may know if this is a common occurance.

Alternatively, you take an Adalat pill, if you have any left and call your
doc if the blood pressure doesn't go down.

If your blood pressure goes back down, I would take all the Mylan pills to
the pharmacist, tell her what happened and ask either they be replaced with
Adalat or you get your money back. And I would go fda.gov, click on Report a
Problem with a product, and file an Adverse Event report. Also, ask you doc
about this at the next visit if your BP stays down.

The stomach pH is low, about 1. This is very acidic. The Mylan labs pills
might dissolve in your stomach faster.

Jeff

> Tom
>

Good advice Jeff ! I was thinking about possible counterfeit drugs.

Good thinking.

The OP should look on the web site for mylan and see if the pills have the right markings: http://www.mylanpharms.com/product/productDetails.aspx?pid=105&query=1 If the pills don't have the proper markings, they're the wrong pills. Could be that the pharmacist pulled the wrong bottle of pills, the pills were packed wrong at the factory, or the pills are conterfeit.If they have the right markings, particularly if the markings look a little different, they could still be counterfeit.

I am not sure why, the Adalat CC has a core or center that is rapid release and a slow release coating. I would have thought the core would be slow release, but the coating would be rapid release (so that the blood levels get to their values fast, and the slow release keeps them there). Anyway, if this is the case, breaking a pill in half may cause a rapid increase in blood levels and dangeriously low blood pressure.

Jeff

Jeff

Bill

--

S Jersey USA Zone 5 Shade
http://www.ocutech.com/ High tech Vison aid
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.

.

Relevant Pages

  • Re: problem with generic nifedipine
    ... Adalat or you get your money back. ... The OP should look on the web site for mylan and see if the pills have the ... the pills don't have the proper markings, ... blood levels and dangeriously low blood pressure. ...
    (sci.med.cardiology)
  • Hypertension by Jeffrey Dach, M.D.
    ... Fifty Million Americans have High Blood Pressure and if you are one of ... then your doctor has you on pressure pills costing 3 billion ... two major types of hypertension with pills that work best for each ... Hypertension is Caused by Renin: ...
    (sci.med)
  • Re: Or Piles - Sunday 11/12 + Mon 12/12
    ... >>> conscious to unconscious on the floor. ... >>> with more pills if he didn't behave, his blood pressure was fine. ... The Bolton Hospital Treadmill does little to help my BP due to them having a ...
    (uk.media.radio.archers)
  • Re: My adopted sister found this story....
    ... My adopted sister found this story of a christian man who had been ... healed of high blood pressure without the use of pills. ...
    (talk.atheism)
  • Re: Or Piles - Sunday 11/12 + Mon 12/12
    ... >> I suspect there are now targets for such things. ... > with more pills if he didn't behave, his blood pressure was fine. ... Except that my Dad is still on some - different - BP medication. ...
    (uk.media.radio.archers)