Re: A Systematic Review and Meta-Analysis of Statin Therapy in Children With Familial Hypercholesterolemia

MarilynMann wrote:
On Jun 25, 2:19 pm, Susan <neverm...@xxxxxxxxxx> wrote:

MarilynMann wrote:

They interest me the way any child abuse does.

Susan


Well, they are just trying to sell their products. The results seem
fairly unimportant. I don't care if they get their LDL down to 70.
In addition, trials of bile acid sequestrants with clinical endpoints
did not show favorable results on total mortality.

Marilyn

Actually, I strongly doubt that any drug company is very interested in studying statins in children with FH so as to boost their profits. Some may have decided to do so for one reason or another, but it's hard to see how there is much upside profit benefit (not that many potential patients), compared to the downside risk that the drugs will turn out to be harmful in children.

So even if you want to take the position that all drug-company sponsored research is tainted, if I were a profit-maximizing drug company I'd rather not study this at all or I'd try to tip the results to show no benefit in children. (I'm not such a conspiracy theorist as to think they would actually do such a thing.)

--
David Rind
drind@xxxxxxxxxxxxxxxxxxxxx
.

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