Re: High-normal fasting blood glucose in non-diabetic range is associated with increased coronary artery calcium burden in asymptomatic men

convicted neighbor Susan wrote:
friend MarilynMann wrote:

High-normal fasting blood glucose in non-diabetic range is associated
with increased coronary artery calcium burden in asymptomatic men


In the same vein:

Ann Intern Med 1998 Apr 1;128(7):524-33



Metabolic risk factors worsen continuously across the spectrum of
nondiabetic glucose tolerance. The Framingham Offspring Study.

Meigs JB, Nathan DM, Wilson PW, Cupples LA, Singer DE
Massachusetts General Hospital, Harvard Medical School, Boston
University School of Public Health, 02114, USA. jmeigs@xxxxxxxxxxxxxxxxxxx

BACKGROUND: Categorical definitions for glucose intolerance imply that
risk thresholds exist, but metabolic risk for type 2 diabetes mellitus
or cardiovascular disease may increase continuously as glucose
intolerance increases. OBJECTIVE: To examine the distributions of the
following metabolic risk factors across the spectrum of glucose
tolerance: overall and central obesity, hypertension, low levels of
high-density lipoprotein cholesterol, and increased triglyceride and
insulin levels. DESIGN: Cross-sectional analysis. SETTING: The
community-based Framingham Offspring Study. PARTICIPANTS: 2583 adults
without previously diagnosed diabetes. MEASUREMENTS: Clinical data;
fasting glucose, insulin, and lipid levels; and glucose and insulin
levels taken 2 hours after oral challenge were collected from 1991 to
1993. Glucose tolerance was determined by 1980 World Health Organization
criteria. Patients with normal glucose tolerance were categorized into
quintiles of fasting glucose. The distributions of each metabolic risk
factor and the metabolic sum of the six risk factors were assessed
across seven categories from the lowest quintile of normal fasting
glucose level through impaired glucose tolerance and previously
undiagnosed diabetes. RESULTS: The mean age of patients was 54 years
(range, 26 to 82 years); 52.7% of patients were women. Glucose tolerance
testing found that 12.7% of patients had impaired glucose tolerance and
4.8% had previously undiagnosed diabetes. Multivariable-adjusted mean
measures of risk factors and odds ratios for obesity, elevated
waist-to-hip ratio, hypertension, low levels of high-density lipoprotein
cholesterol, elevated triglyceride levels, and hyperinsulinemia showed
continuous increases across the spectrum of nondiabetic glucose
tolerance. Although a threshold effect near the upper range of
nondiabetic glucose tolerance could not be ruled out for triglyceride
levels in men and for insulin levels 2 hours after oral challenge in men
and women, no other metabolic risk factors showed clear evidence of
thresholds for increased risk. CONCLUSIONS: Metabolic risk factors for
type 2 diabetes mellitus and for cardiovascular disease worsen
continuously across the spectrum of glucose tolerance categories,
beginning in the lowest quintiles of normal fasting glucose level.

This is consistent with VAT being pathological starting with the very
first ounce of it.

It is only when we are hungry that the body gets rid of VAT

Be hungry... be healthy... be blessed:

http://HeartMDPhD.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

.

Relevant Pages

  • Re: Advice on cholesterol? Effect of taking "extra" olive oil?
    ... I'd never had an fbg above 109, or lower than 109 for 10 years. ... after you scared me half to death, a two-hour reading on the glucose tolerance test of 140 or below is considered normal. ... Categorical definitions for glucose intolerance imply that risk thresholds exist, but metabolic risk for type 2 diabetes mellitus or cardiovascular disease may increase continuously as glucose intolerance increases. ...
    (sci.med.cardiology)
  • Re: Association between Carbohydrate Intake and Serum Lipids
    ... higher total carbohydrate intake, percentage of calories from carbohydrate, glycemic index and/or glycemic load are related to lower high-density lipoprotein cholesterol and higher serum triacylglycerol levels, while higher total carbohydrate intake and/or GL ... Categorical definitions for glucose intolerance imply that risk thresholds exist, but metabolic risk for type 2 diabetes mellitus or cardiovascular disease may increase continuously as glucose intolerance increases. ... OBJECTIVE: To examine the distributions of the following metabolic risk factors across the spectrum of glucose tolerance: overall and central obesity, hypertension, low levels of high-density lipoprotein cholesterol, and increased triglyceride and insulin levels. ...
    (sci.med.cardiology)
  • Re: Can dieting cause diabetes
    ... The fact is that cardiac mortality risk rises all along the normal spectrum, ... Metabolic risk factors worsen continuously across the spectrum of nondiabetic glucose tolerance. ... Categorical definitions for glucose intolerance imply that risk thresholds exist, but metabolic risk for type 2 diabetes mellitus or cardiovascular disease may increase continuously as glucose intolerance increases. ...
    (alt.support.diabetes)
  • Re: Very low-carb diets work for men and upper body fat
    ... Categorical definitions for glucose intolerance imply that risk ... risk factors across the spectrum of glucose tolerance: ... School of Clinical Medicine, UK, collected>data on all-cause mortality ...
    (sci.med.nutrition)
  • Re: Can dieting cause diabetes
    ... briefly after a high carb meal even for "normals". ... glucose tolerance, blood glucose peaks and insulin peaks vary ... is that cardiac mortality risk rises all along the normal spectrum, ...
    (alt.support.diabetes)
Loading