Re: HYVET stopped early

On Aug 9, 10:30 am, David Rind <dr...@xxxxxxxxxxxxxxxxxxxxx> wrote:
bigvince wrote:
On Aug 8, 10:25 am, David Rind <dr...@xxxxxxxxxxxxxxxxxxxxx> wrote:

No, it wasn't. A relative risk of 1.01 with a CI of 0.89-1.15 is not a
slight increase in mortality risk and you don't get to claim it as such,
any more than I can pretend that the RR of 0.99 in the Cochrane
meta-analysis was a slight decrease in mortality.

--
David Rind

You are correct . In this study atenolol v placebo moratality was
unchanged ; but there are anaysis that indicate atenolol increases
mortality rates when compared to other active treatments. Let me ask
again

At best this drug has little value and less evidence to support its
use in the control hypertension. Studies have linked it to an
increased risk of diabetes.It has unpleasant and sometimes serious
side effects. It provides very little [ if any ] benefit to the
patient . In every comparison trail it loses. Doctors her still
widely
prescibe it. Why?

Thanks Vince

No, the studies don't indicate that atenolol "increases mortality"
compared to other active treatments. The studies indicate that atenolol
does not decrease mortality as much as those other treatments.

The studies show that
A. Atenelol has no effect on mortality.Here I think we agree . So it
does not reduce mortality at all. I think you phasing on this creates
the impression that atenolol decreases mortality rates it does not

B.Other drugs ARBS Ace inhibitors ect may reduce mortality rates .

The statement atenolol increases mortality rates as compared to other
classes of drugs is true.

Again why is it still widely used at least in the US in the UK steps
have been taken to assure it is no better than the 5th option.

Thanks Vince

.

Relevant Pages

  • Re: HYVET stopped early
    ... Taking atenolol does not increase mortality rates. ... The Vasodilatory Beta-blockers. ... effective in reducing central aortic pressure. ...
    (sci.med.cardiology)
  • Re: HYVET stopped early
    ... hypertension raises mortality, ... Meta-analyses of antihypertensive therapy with atenolol show that it ... and has often been used as a reference drug in randomised ...
    (sci.med.cardiology)
  • Re: beta-blockers
    ... I think for at least several years we've had evidence that beta blockers ... are not a good first choice for hypertension, since they do not seem to ... reduce mortality as much as other treatments. ... As a never said beta blockers and only referred to atenolol as ...
    (sci.med.cardiology)
  • Re: HYVET stopped early
    ... hypertension raises mortality, ... Meta-analyses of antihypertensive therapy with atenolol show that it ... and has often been used as a reference drug in randomised ...
    (sci.med.cardiology)
  • Re: HYVET stopped early
    ... slight increase in mortality risk and you don't get to claim it as such, ... meta-analysis was a slight decrease in mortality. ... In this study atenolol v placebo moratality was ... There is no evidence that atenolol increases mortality it just doesn't work as well as some other medications used for hypertension. ...
    (sci.med.cardiology)