Re: Looking Past Blood Sugar to Survive With Diabetes



On Aug 20, 10:50 am, William Wagner <-----william...@xxxxxxxxx> wrote:
http://www.nytimes.com/2007/08/20/health/20diabetes.html?_r=1&hp&oref...
gin

or  http://preview.tinyurl.com/2tklvf

No Mention of HDL !  Mentions BP but no mention of Beta blockers effect
on BG.

Bill who is thinking that any meds  have pluses and Minus.  Sort of like
high gloss paint has less durability and High durability has low gloss
think road paint.

Below some snippets that perhaps Susan  and  and Jim can weigh in on.

...........................

With cholesterol, the guidelines say that levels of LDL cholesterol, the
form that increases heart disease risk, should be below 100 milligrams
per deciliter and, if possible, 70 to 80. Yet, Dr. Brownlee said,
diabetes patients with LDL cholesterol levels of 100 to 139 often are
told that their levels ‹ ideal for a healthy person without diabetes ‹
are terrific.
³Many practicing doctors just don¹t know that an LDL cholesterol number
that is normal for someone without diabetes is not normal for someone
with diabetes,² he said.


...The word normal seems just a little strange here the guidelines
suggest levels that are almost always only attainable with drug
therapy that is hardly a 'normal' level

lA word about the way.the guidelines where set.from USA today

http://www.usatoday.com/news/health/2004-10-16-panel-conflict-of-interest_x..htm

"Cholesterol guidelines become a morality play
The Associated Press
They led influential medical groups, starred at prestigious meetings,
published in top journals and were undisputed giants in their field.
But when these famous doctors advised the government recently on new
cholesterol guidelines for the public, something else they had in
common wasn't revealed.

Eight of the nine were making money from the very companies whose
cholesterol-lowering drugs they were urging upon millions more
Americans. Two own stock in them. Two others went to work for drug
companies shortly after working on the guidelines. Another was a
senior government scientist who moonlights for 10 companies and even
serves on one of their boards.' the story also notes

"Christopher Seymour, executive director of the National Lipid
Association, a group that promotes cholesterol control and is largely
funded by drug companies, has six of the nine guideline doctors on his
board.

"Who in America is going to write these guidelines if you don't go to
the thought leaders? Should I call Dr. X in the middle of Peoria? What
gives them credentials to be on my board?" he asked.

But at the University of Illinois in Peoria, they think quite a lot of
Dr. Frank Gold, who in 30 years as a cardiologist has taken no
consulting or lecture fees from industry.

"I'm squeaky-clean," he says, and "would jump at the opportunity" to
serve on a guidelines panel. "There are tons of people like me, and
they're even in places like Des Moines." and further notes that
"

Financial conflicts aren't the only danger. "Group think" can set in
when a panel doesn't include people who can look at the science with
different views than cardiologists.

"These folks made their careers on being aggressive on treating risk
factors," but internal medicine doctors might feel differently, said
Dr. Harlan Krumholz, who runs a center for medical outcomes research
at Yale University. "

...................

Complex Regimens
Before he left the hospital, Mr. Smith¹s doctors told him about his new
diabetes regimen: a statin to drive his cholesterol level very low, two
drugs to lower his blood pressure, an aspirin, insulin and two drugs to
reduce his blood sugar levels. That new list of drugs was what he should
have been taking all along.

And on that recommended list at least according to the last
guidelines beta blockers which can increase IR and cause diabetes it
is still on the list of meds that should used for 'tight blood
pressure control. Diuretics which also can cause diabetes. But just do
not worry to treat any problems why we still have on the approved list
Advandia the number one drug in it's class. Unfortunatly its effect on
heart attacks might not be optimal '[some suggest it might actaully
increase them ]
but it is still on that list to reduce blood sugar levels and follow
the guidelines]

And it is not just that many diabetes patients are overweight, as people
with Type 1 diabetes, who often are thin, also have a high risk of heart
disease. There is something about diabetes itself, researchers say, that
leads to high levels of LDL cholesterol and a form of LDL cholesterol
particles that is particularly dangerous. Diabetes also leads to
increased levels of triglycerides, which are fats in the blood that
increase heart disease risk, and in diabetes is linked to high blood
pressure.

.................

The key to saving lives is to reduce levels of LDL cholesterol to below
100 and also control other risk factors like blood pressure and smoking.
The cholesterol reduction alone can reduce the very high risk of heart
attacks and death from cardiovascular disease in people with diabetes by
30 percent to 40 percent, Dr. Cleeman said. And clinical trials have
found that LDL levels of 70 to 80 are even better for people with
diabetes who already have overt heart disease.

Ldl levels have not been shown to increase the risk of heart diesese
nor has lowering ldl levels with statins in primary prevention been
shown to save lives. Many studies old and new have shownconfirmed
those facts .Better indicators are the ratio of sub fractions of ldl
and hdl of the waist hip ratio .LDL is a oversimplification that sells
statins but does not reflect the current science. The piece minimised
the effect of diet and exercise many feel that type 2 diabetes is
largely preventable if lifestyle changes are made.

Thanks Vince

.



Relevant Pages

  • Re: NYT article on diabetes T2
    ... Is atherosclerosis in diabetes and impaired fasting glucose driven by elevated LDL cholesterol or by decreased HDL cholesterol? ... To evaluate the atherogenicity of lipids in coronary patients with normal fasting glucose, impaired fasting glucose, and type 2 diabetes. ...
    (alt.support.diabetes)
  • Re: The Optimum LDL is about 3,NOT LOWER......
    ... Independent associations between low-density lipoprotein cholesterol and cancer among patients with type 2 diabetes mellitus ... LDL cholesterol were associated with elevated risk of cancer. ...
    (alt.support.diabetes)
  • Guidelines for People w. Diabetes or Pre-Diabetes who are Overweight or Obese
    ... Joslin Diabetes Center Announces New Nutrition Guidelines for People with ... Type 2 Diabetes or Pre-Diabetes who are Overweight or Obese ... cardiovascular health and reduce body fat. ... Approximately 40 percent of a person's daily calories should ...
    (sci.med.nutrition)
  • Re: a primer on statins?
    ... study because of my cholesterol levels. ... use of non-study statins and similar reduction in LDL cholesterol, ... type of diabetes, although there were very few patients with type 1 diabetes ... pressure lowering drugs reduced the risk of strokes by about 25%, coronaries ...
    (alt.support.diabetes)
  • Re: What cxercise, vitamins, or food needed for diabetes/cardio risk individual?
    ... more than any diabetes drug. ... Cinnamon improves glucose and lipids of people with type 2 diabetes. ... cholesterol, and LDL cholesterol levels in people with type 2 diabetes. ... and total cholesterol levels; ...
    (sci.med.nutrition)