Re: Do drugs {including statins} and procedures benefit women and men equally?



bigvince <Vince.Miraglia@xxxxxxxxx> wrote in part:

ASCOT-LLA (2003)
ASCOT-LLA (Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering
Arm) was designed to assess the benefits of atorvastatin (Lipitor)
versus a placebo in patients who had high blood pressure with average
or lower-than-average cholesterol concentrations and at least three
other cardiovascular risk factors.48 The trial was originally planned
for five years but was stopped after a median follow-up of 3.3 years
because of a significant reduction in cardiac events. Lipitor did
reduce total myocardial infarction and total stroke; however, total
mortality was not significantly reduced. In fact, women were worse off
with treatment. The trial report stated that total serious adverse
events "did not differ between
patients assigned atorvastatin or placebo," but did not supply the
actual numbers of serious events.

This was for primary prevention.
--
Jim Chinnis Warrenton, Virginia, USA
.



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