Re: Do drugs {including statins} and procedures benefit women and men equally?

On Sep 11, 4:02 pm, Jim Chinnis <jchin...@xxxxxxxxxxxxxxxx> wrote:
bigvince <Vince.Mirag...@xxxxxxxxx> wrote in part:

ASCOT-LLA (2003)
ASCOT-LLA (Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering
Arm) was designed to assess the benefits of atorvastatin (Lipitor)
versus a placebo in patients who had high blood pressure with average
or lower-than-average cholesterol concentrations and at least three
other cardiovascular risk factors.48 The trial was originally planned
for five years but was stopped after a median follow-up of 3.3 years
because of a significant reduction in cardiac events. Lipitor did
reduce total myocardial infarction and total stroke; however, total
mortality was not significantly reduced. In fact, women were worse off
with treatment. The trial report stated that total serious adverse
events "did not differ between
patients assigned atorvastatin or placebo," but did not supply the
actual numbers of serious events.

This was for primary prevention.


Jim heres my original comment

"As some studies have suggested that statins also have even less
value
in women does the one size fits all approach in the ATP guidelines
need rethinking. '

Where in that comment do you see a restiction on studys on primary
prevention . The Ascott study is relavent to my comment .Thanks
Vince

.

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