Re: Do you recommend Arestin for 5mm pockets?

george1234 wrote:

On Tue, 15 Nov 2005 15:59:53 GMT, "Amatus Cremona"
<Nicola@xxxxxxxxxxxxxx> wrote:


modest gains


Clinically significant ? 




Hafajee says meta analysis indicates it is clinically significant
(slide 19)

http://dentalschool.bu.edu/ce/spring2005/OralHealth/HaffajeePresentation_files/frame.htm

"Meta-analysis indicated that antibiotics provided significantly
better AL "gain" of 0.3-0.4 mm at 6 mos. post-therapy than the
control groups not receiving antibiotic"

This benefit is seen at 12 months (slide 24)

The benefit depends on initial pocket depth, the greater the depth the
greater the benefit (slde 25 and 26)


I think that what AC means is clinically significant, and not statistically significant. It is doubtful that a gain in attachment level of .3-.4 mm is going to make a significant difference to the long-term prognosis of a tooth (though it may well be highly significant statistically).

Steve

--
Mark & Steven Bornfeld DDS
http://www.dentaltwins.com
Brooklyn, NY
718-258-5001
.

Relevant Pages

  • Re: Do you recommend Arestin for 5mm pockets?
    ... Hafajee says meta analysis indicates it is clinically significant ... post-therapy than the ... The benefit depends on initial pocket depth, ... It is doubtful that a gain in attachment level of .3-.4 mm is going to make a significant difference to the long-term prognosis of a tooth. ...
    (sci.med.dentistry)
  • Re: Do you recommend Arestin for 5mm pockets?
    ... It is doubtful that a gain in attachment level of .3-.4 mm is going to make a significant difference to the long-term prognosis of a tooth. ... I've seen other studies, using pocket depth as the metric, that show a ...
    (sci.med.dentistry)