Re: lichen planus
- From: jay <jaym1212@xxxxxxxxxxx>
- Date: 23 May 2007 10:46:04 -0700
Healing of oral lichenoid lesions after replacing amalgam
restorations: a systematic review.Issa Y, Brunton PA, Glenny AM,
Duxbury AJ.
University Dental Hospital of Manchester, England, UK.
OBJECTIVE: We sought to systematically review the literature related
to oral lichenoid lesions (OLLs) and amalgam restorations. STUDY
DESIGN: Cohort and case-controlled studies (no randomized controlled
trials or controlled clinical trials available) were reviewed with
respect to inclusion criteria and data on patients with OLLs,
treatment interventions, and the measurement of outcomes. RESULTS:
Fourteen cohort and 5 case-controlled trials met the criteria. The
study population consisted of 1158 patients (27% male and 73% female;
age range, 23-79 years). From 16% to 91% of patients had positive
patch test results for at least 1 mercury compound. Of 1158 patients,
636 had to have their restorations replaced. The follow-up period
ranged from 2 months to 9 1/2 years. Complete healing ranged from
37.5% to 100%. The greatest improvements were seen in lesions in close
contact with amalgam. CONCLUSIONS: Protocols must be standardized to
obtain valid results. The replacement of amalgam restorations can
result in the resolution or improvement of OLLs. Patch testing seems
to be of limited value. The topographic relationship between an OLL
and an amalgam restoration is a useful--but not conclusive--marker.
PMID: 15529127 [PubMed - indexed for MEDLINE]
.
- References:
- lichen planus
- From: John & Ninetta
- lichen planus
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