Re: Hamer cancer therapy
From: J (startle_at_anon.anon)
Date: 08/03/04
- Next message: heinzA: "High CA 125 values without ovaries?"
- Previous message: J: "Re: Hoxsey treatment"
- Maybe in reply to: Happy Dog: "Re: Hamer cancer therapy"
- Messages sorted by: [ date ] [ thread ]
Date: Mon, 02 Aug 2004 20:11:12 -0400
john wrote:
> Goto:
http://www.mdanderson.org/departments/CIMER/
Biologic/Organic/Pharmacologic Therapies:
MTH-68/Newcastle Disease Virus
Caution: Some complementary agents or therapies may be useful for cancer
patients; however, some may be harmful in certain situations. M. D. Anderson
Cancer Center cautions patients to consult with their oncologist before
attempting to use any agents or therapies referenced on these pages. Inclusion
of an agent, therapy, or resource on this CIMER web site does not imply
endorsement by M. D. Anderson Cancer Center.
(Summary is based upon review by the National Cancer Institute updated as of
3/5/2004.)
Description
Newcastle Disease Virus is a virus that causes an often-fatal disease in birds,
notably in chickens. Although it can also infect humans, the result is generally
only mild flu-like symptoms, conjunctivitis and/or laryngitis. It has been
investigated as an anti-cancer therapy because of its perceived ability to
replicate (multiply) better in cancer cells than in normal cells.
The many different strains of Newcastle Disease Virus are classified as lytic or
non-lytic for human cells. Both types of strains can kill cancer cells, but
lytic strains have the potential to kill more quickly because they damage the
plasma membrane of infected cells. Nonlytic strains kill by interfering with
cell metabolism. Both strains can stimulate the immune system and are used in
the development of oncolysates (extracts of infected cancer cells used as
vaccines).
Numerous in vitro studies (laboratory studies of cells) have shown that certain
strains of this virus replicate better in some types of cancer cells than in
others. Specific types and cancer cells affected are listed in the review by the
National Cancer Institute (NCI) which may be accessed through the link at the
bottom of this page.
Human trials of one strain of Newcastle Disease Virus, MTH-68 ("More Than
Hope"), have been largely conducted in Hungary. A different strain, PV701, has
been studied in one phase I dose finding trial in the U.S.
The NCI review was not able to reach any conclusions concerning the
effectiveness of Newcastle Disease Virus in the treatment of cancer because of
limitations of the studies that have been conducted in humans so far.
Dose
Appropriate doses must be determined through consultation with physicians.
How it is taken
In human studies, Newcastle Disease Virus has been administered by subcutaneous
or intradermal injection. Other methods such as inhalation and injection into
the colon through a colostomy have also been employed.
Side effects
Reported side effects have been generalized mild flu-like symptoms,
conjunctivitis, laryngitis, fever and headache.
Possible risks
According to the NCI review, side effects of inflammation and edema may have
contributed to the death of one patient. In some situations, however,
inflammation and edema have been attributed to concurrently administered
interleukin-2 immunotherapy.
Important Advice
To avoid potential interactions, be sure to let your health care provider know
if you use this or any other type of complementary therapy.
- Next message: heinzA: "High CA 125 values without ovaries?"
- Previous message: J: "Re: Hoxsey treatment"
- Maybe in reply to: Happy Dog: "Re: Hamer cancer therapy"
- Messages sorted by: [ date ] [ thread ]
Relevant Pages
|
