Re: Mitamycin C reaction

From: madiba (down_at_thekraal.com)
Date: 08/20/04 

Date: Sat, 21 Aug 2004 00:12:53 +0200

DON GATES <dpagates@verizon.net> wrote:

> I had TCC of the bladder. Upon cystoscopy and tumor removal, mitamycin C was
> flushed into the bladder until I urinated some 30 minutes after.
>
> I had extreme pain in the penis 24/7, painful urination, hematuria and
> passing clots. To make this short, another cysto was done 43 days after the
> first and my urologist and pathologist (the path happens to be my boss as
> well) came up with an severe allergic reacton to the mitamycin. My urologist
> said he's never seen a bladder so irritated. Been on benedryl, did the
> prednisone dose pak, urimax and hydrocodone pain killers. None really worked
> but about a month later I seem to be better. Hurts when I urinate some, not
> all the time and not so severe. But the pain was always in my penis, not the
> bladder/lower stomach area.
>
> Is there really such a thing as referred pain in this situation? The bladder
> is ornery as a hornet's nest but my penis feels the pain.
>
> Any comments appreciated. Just sems I shouldn't have went through all this.
> Hmmmmm.

Unusual presentation of a mytomycin allergy...
Other possibility: Post-op infection.
As far as the location of the referred pain goes, I've seen a similar
problem in patients with kidney stones on their way down the ureter. 

-- 
madiba

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