Re: Use of Oxaliplatin for Cholangiocarcinoma?
- From: J <Hiss-ss-ss@xxxxxxxxxxx>
- Date: Tue, 07 Jun 2005 15:51:52 -0400
farrell77 wrote:
> "Steph" <steph@xxxxxxxxxxxxxxxxx> wrote in message
> news:yttne.1538978$6l.772567@xxxxxxxxxxx
> >
> > "farrell77" <farrell77@xxxxxxxxxxxxxxxxxx> wrote in message
> > news:Ifone.503$Wk4.11300@xxxxxxxxxxxxxxxxxx
> > > Can anyone provide references or data that could help persuade an
> > > insurance
> > > company to pay for oxaliplatin to treat cholangiocarcinoma? Insurance
> > > claims have been denied, apparently on grounds that this is not a standard
>
> > > treatment. Thanks.
> > >
>
> >
> > What do you expect oxaliplatin to achieve?
>
> Options and time are running short, and it's been suggested by several
> doctors
> (as a treatment for my brother).
>
> Here's one abstract I received from a doctor at a major cancer center:
>
> A phase II study of Oxaliplatin (O) and Gemcitabine (G) first line
> chemotherapy
> in patients with advanced biliary tract cancers. Abstract No: 4132
It's a small trial and first line Phase II - presumably your brother's had
other treatments? Including gemcitabine (Gemzar) ?
http://www.cancerguide.org/small_trial_stats.html
Why Good Results From Small Trials Often Don't Pan Out
It's been in Phase III (palliative) for 2 years now for pancreatic; a cancer
that usually carries a similar prognosis.
http://www.clinicaltrials.gov/ct/gui/show/NCT00075452
This randomized phase III trial is studying gemcitabine and oxaliplatin to see
how well they work compared to gemcitabine alone in treating patients with
locally advanced or metastatic unresectable pancreatic adenocarcinoma.
How is your brother, Bob?
J
.
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