Nanobacteria Infection & Ovarian Cancer
- From: "NanoBiotech Reviews" <gmezo@xxxxxxxxxxxxxx>
- Date: 9 Jun 2005 13:04:21 -0700
APMIS. 2003 Oct;111(10):951-4. Related Articles, Links
Nanobacteria promote crystallization of psammoma bodies in ovarian
cancer.
Sedivy R, Battistutti WB.
Department of Clinical Pathology, University Hospital Vienna, Austria.
roland.sedivy@xxxxxxxxxxxxxx
Serous papillary adenocarcinomas of the ovary are often associated with
microcalcifications, namely psammoma bodies. Archebacteria such as
nanobacteria are, for example, involved in kidney stone formation.
Nanobacteria deserve close scrutiny as their cytotoxicity and ability
to cross the placenta present a potential clinical risk. In this study
we investigated whether nanobacteria are associated with psammoma
bodies in ovarian cancer. We identified in all seven carcinomas with
multiple psammoma body nanobacterial antigens in histological specimens
and in the ascitic fluid. Control cases of adenocarcinomas without such
calcifications did not present nanobacterial antigens. This finding
indicates that apart from non-malignant conditions, nanobacteria could
also be found in cancer. Hence, nanobacterial infection may be of
clinical importance as these bacteria are related to microcalifications
in ovarian cancer.
PMID: 14616547 [PubMed - indexed for MEDLINE]
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