New Drug Might Help Prevent Breast Cancer

Comment: Ridiculous?
J

<http://www.forbes.com/lifestyle/health/feeds/hscout/2005/11/11/hscout529015.html>

New Drug Might Help Prevent Breast Cancer
-- Robert Preidt

FRIDAY, Nov. 11 (HealthDay News) -- A drug currently undergoing clinical
trials for use in treating a postmenopausal condition called vaginal
atrophy may also help prevent breast cancer, according to two preliminary
studies.

The first study found that the drug, ospemifene, inhibited breast cancer
development in mice exposed to a carcinogen. The second study found that
ospemifene inhibited the growth and progression of pre-malignant breast
lesions in mice.

Ospemifene belongs to a class of drugs called selective estrogen receptor
modulators, which includes tamoxifen and raloxifen.

"These reports indicate that prevention of breast cancer may be another
benefit of the use of ospemifene. The findings are very encouraging,"
Michael W. DeGregorio, a professor of medicine at the University of
California, Davis, said in a prepared statement.

DeGregorio, a co-author on both papers, spent 20 years developing
ospemifene in collaboration with a Finnish researcher. The drug is
expected to enter Phase III clinical testing in the United States next
year for treatment of vaginal atrophy, a common condition in
postmenopausal women.

The two new studies appear in the November issue of the Journal of Steroid
Biochemistry and Molecular Biology and the December issue of the journal
Breast Cancer Research.

.

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