Re: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) may be used prevent cancer in future

sylvester wrote:
Mayo Clinic Cancer Center has begun three clinical studies looking at
the use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) to prevent
cancer -- colon, esophageal or lung.

This is an extremely bad idea as NSAIDs are a very dangerous and deadly
class of medications.

"Conservative calculations estimate that approximately 107,000
patients are hospitalized annually for nonsteroidal anti-inflammatory
drug (NSAID)-related gastrointestinal (GI) complications and at least
16,500 NSAID-related deaths occur each year among arthritis patients
alone. The figures of all NSAID users would be overwhelming, yet the
scope of this problem is generally under-appreciated."

Singh Gurkirpal, MD, "Recent Considerations in Nonsteroidal
Anti-Inflammatory Drug Gastropathy", The American Journal of
Medicine, July 27, 1998, p. 31S


"It has been estimated conservatively that 16,500 NSAID-related
deaths occur among patients with rheumatoid arthritis or osteoarthritis
every year in the United States. This figure is similar to the number
of deaths from the acquired immunodeficiency syndrome and considerably
greater than the number of deaths from multiple myeloma, asthma,
cervical cancer, or Hodgkin's disease. If deaths from
gastrointestinal toxic effects from NSAIDs were tabulated separately in
the National Vital Statistics reports, these effects would constitute
the 15th most common cause of death in the United States. Yet these
toxic effects remain mainly a "silent epidemic," with many
physicians and most patients unaware of the magnitude of the problem.
Furthermore the mortality statistics do not include deaths ascribed to
the use of over-the-counter NSAIDS."

Wolfe M. MD, Lichtenstein D. MD, and Singh Gurkirpal, MD,
"Gastrointestinal Toxicity of Nonsteroidal Anti-inflammatory
Drugs", The New England Journal of Medicine, June 17, 1999, Vol. 340,
No. 24, pp. 1888-1889.

.

Relevant Pages

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