Re: Anyone with experience with Curcumin?



JoeC wrote:

I hear it is a good anti-cancer herb and it is mentioned in many
nutrition books


Apparently MD Anderson is running studies.
Their CIMER web page says that:
There is no current credible human studies.

and
Interactions with Drugs

Anticoagulants: Based on laboratory and animal studies, turmeric may
inhibit platelets in the blood and increase the risk of bleeding caused by
other drugs. Some examples include aspirin, anticoagulants ("blood
thinners") such as warfarin (Coumadin®) or heparin, anti-platelet drugs
such as clopidogrel (Plavix®) and non-steroidal anti-inflammatory drugs
such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).

Anti-hyperglycemics, insulin: Based on animal data, turmeric may lower
blood sugar and therefore may have additive effects with diabetes
medications.

Anti-inflammatory drugs: In animals, turmeric protects against stomach
ulcers caused by non-steroidal anti-inflammatory drugs (NSAIDs) such as
indomethacin (Indocin®), and against heart damage caused by the
chemotherapy drug doxorubicin (Adriamycin®).

Cholesterol-lowering drugs: Turmeric may lower blood levels of low-density
lipoprotein (LDL or ?bad? cholesterol) and increase high-density
lipoprotein (HDL or ?good? cholesterol). Thus, turmeric may increase the
effects of cholesterol-lowering drugs such as lovastatin (Mevacor®) or
atorvastatin (Lipitor®).

Cytochrome P450-metabolizing drugs: Based on animal studies, turmeric may
interfere with the way the body processes certain drugs using the liver?s
?cytochrome P450? enzyme system. As a result, the levels of these drugs
may be increased in the blood, and may cause increased effects or
potentially serious adverse reactions. If you are using any medications,
check the package insert and speak with your healthcare professional or
pharmacist about possible interactions.

Interactions with Herbs and Dietary Supplements

Anticoagulants: Based on animal studies, turmeric may increase the risk of
bleeding when taken with herbs and supplements that are believed to
increase the risk of bleeding. Multiple cases of bleeding have been
reported with the use of Ginkgo biloba, some cases with garlic and fewer
cases with saw palmetto. Numerous other agents may theoretically increase
the risk of bleeding, although this has not been proven in most cases.
Some examples include alfalfa, American ginseng, angelica, anise, Arnica
montana, asafetida, aspen bark, bilberry, birch, black cohosh,
bladderwrack, bogbean, boldo, borage seed oil, bromelain, capsicum, cat's
claw, celery, chamomile, chaparral, clove, coleus, cordyceps, danshen,
devil?s claw, dong quai, evening primrose, fenugreek, feverfew,
flaxseed/flax powder (not a concern with flaxseed oil), ginger, grapefruit
juice, grapeseed, green tea, guggul, gymnestra, horse chestnut,
horseradish, licorice root, lovage root, male fern, meadowsweet,
nordihydroguairetic acid (NDGA), onion, papain, Panax ginseng, parsley,
passionflower, poplar, prickly ash, propolis, quassia, red clover, reishi,
Siberian ginseng, sweet clover, rue, sweet birch, sweet clover, vitamin E,
white willow, wild carrot, wild lettuce, willow, wintergreen and yucca.

Cytochrome P450-metabolizing drugs: Based on animal studies, turmeric may
interfere with the way the body processes certain herbs or supplements
using the liver?s "cytochrome P450" enzyme system. As a result, the levels
of other herbs or supplements to be too high in the blood. It may also
alter the effects that other herbs or supplements possibly have on the
P450 system, such as bloodroot, cat?s claw, chamomile, chaparral,
chasteberry, damiana, Echinacea angustifolia, goldenseal, grapefruit
juice, licorice, oregano, red clover, St. John?s wort, wild cherry and
yucca.

Cholesterol-lowering drugs: Turmeric may lower blood levels of low-density
lipoprotein (LDL or "bad" cholesterol) and increase high-density
lipoprotein (HDL or "good" cholesterol). Thus, turmeric may increase the
effects of cholesterol-lowering herbs or supplements such as fish oil,
garlic, guggul or niacin.

Anti-hyperglycemics, insulin: Based on animal data, turmeric may lower
blood sugar. Check with your health care professional before starting
turmeric if you are taking other herbs or supplements or medications for
diabetes."

They've got some animal date, but none for humans.
You can read the whole thing by typing CIMER into your search engine. You
get to MDAnderson webpage, for alternative theories, then select
Herbal/Plant Biologic Therapies , then Curcurin/Tumeric.

The FDA just shot down the tomato /lycopene theory.
J


.



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