Low cholesterol 'link' to cancer
- From: E.Nigma <NoReply@xxxxxx>
- Date: 24 Jul 2007 18:23:53 -0000
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Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/6911530.stm
People who significantly cut their cholesterol levels with statins
may raise the risk of cancer, a study says.
The study of 40,000 people found those with little of the "bad"
cholesterol LDL saw one more cancer case per 1,000 than those with
higher levels.
The Boston-based researchers could not say if this was a side-effect
of the statin or due to the low cholesterol.
They also write in the Journal of the American College of Cardiology
that the benefits of statins outweigh the risks.
"The analysis doesn't implicate the statin in increasing the risk of
cancer," says lead author Richard Karas of Tufts University School of
Medicine in Boston. "The demonstrated benefits of statins in lowering
the risk of heart disease remain clear.
"However certain aspects of lowering LDL with statins remain
controversial and merit further research."
Reservations
Researchers looked at the summary data from 13 trials of people
taking statins - a total of 41,173 patients.
These findings do not change the message that the benefits of taking
statins greatly outweigh any potential risks
British Heart Foundation
They examined the relationship between low, medium and high doses of
statins and rates of newly diagnosed cancer.
Higher rates of the disease - which were not of any type or location
- - were observed in the group with the lower levels.
The authors noted their findings were particularly important at a
time when more and more trials show significant reductions in LDL
levels can greatly benefit cardiovascular health.
Cancer Research UK was wary of the study.
Cancer information officer Dr Alison Ross said: "The findings of this
study should be treated with caution - it is based on summary data
from previous trials and, as the authors point out themselves, it
does not prove that low LDL cholesterol levels can increase cancer
risk.
"Much more research is needed before any firm conclusions can be
made."
The British Heart Foundation said they had long known of a
relationship between low cholesterol and cancer.
"While this highlights an association between low levels of LDL and
cancer, this is not the same as saying that low LDL or statin use
increases the risk of cancer," said June Davison, cardiac nurse.
"There is overwhelming evidence that lowering LDL cholesterol through
statins saves lives by preventing heart attacks and strokes. These
findings do not change the message that the benefits of taking
statins greatly outweigh any potential risks."
================
E.
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