Alcohol, Diabetes, Hepatitis Up Liver Cancer Risk

From: Roman Bystrianyk (rbystrianyk_at_gmail.com)
Date: 09/18/04 

Date: 17 Sep 2004 17:10:33 -0700

http://www.healthsentinel.com/news.php?event=news_print_list_item&id=249

Will Boggs, MD, "Alcohol, Diabetes, Hepatitis Up Liver Cancer Risk",
Reuters, September 17, 2004,
Link: http://www.reuters.com/newsArticle.jhtml?type=healthNews&storyID=6268690

Heavy alcohol use, diabetes, and viral hepatitis combine
synergistically to raise the risk of developing liver cancer,
according to a new report.

As lead investigator Dr. Jian-Min Yuan told Reuters Health,
"Physicians should be aware of the increased risk of liver cancer for
their patients who are obese and possess additional risk factors such
as hepatitis virus infection and heavy alcohol consumption."

Yuan from the University of Southern California, Los Angeles, and
colleagues examined viral and non-viral risk factors for liver cancer
among 295 patients with the disease and 435 matched cancer-free
"controls."

As expected, hepatitis B virus and hepatitis C virus infections were
both risk factors for liver cancer, the authors report, with hepatitis
C exerting a stronger effect.

Compared with non-drinkers, moderate drinkers actually had a 40
percent lower risk of liver cancer, but heavy alcohol consumption
significantly increased the risk. In addition, a history of diabetes
increased the risk of liver cancer almost three-fold.

Heavy drinking in those with diabetes raised the likelihood of
developing liver cancer more than 17-fold, the team reports, while the
combinations of viral hepatitis and diabetes or viral hepatitis and
heavy alcohol consumption each increased the risk for liver cancer
about 48 times.

"These factors," the researchers conclude in the medical journal
Cancer, "are likely contributors to the rising incidence of liver
cancer in the U.S."

Screening people with these risk factors, Yuan added "will help in
early detection of liver cancer, and liver cancer in the early stage
is manageable and even treatable."

SOURCE: Cancer, September 1, 2004.

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