lyme and pregnancy

From: zipzip (mcpucho_at_hotmail.com)
Date: 08/27/04 

Date: 26 Aug 2004 19:49:41 -0700

€ TITLE:
Lyme disease during pregnancy.
AUTHORS:
Markowitz LE; Steere AC; Benach JL; Slade JD; Broome CV
SOURCE:
JAMA 1986 Jun 27;255(24):3394-6
ABSTRACT:
Lyme disease is an increasingly recognized tick-borne illness caused
by a spirochete, Borrelia burgdorferi. Because the etiologic agent of
Lyme disease is a spirochete, there has been concern about the effect
of maternal Lyme disease on pregnancy outcome. We reviewed cases of
Lyme disease in pregnant women who were identified before knowledge of
the pregnancy outcomes. Nineteen cases were identified with onset
between 1976 and 1984. Eight of the women were affected during the
first trimester, seven during the second trimester, and two during the
third trimester; in two, the trimester of onset was unknown. Thirteen
received appropriate antibiotic therapy for Lyme disease. Of the 19
pregnancies, five had adverse outcomes, including syndactyly, cortical
blindness, intrauterine fetal death, prematurity, and rash in the
newborn. Adverse outcomes occurred in cases with infection during each
of the trimesters. Although B burgdorferi could not be implicated
directly in any of the adverse outcomes, the frequency of such
outcomes warrants further surveillance and studies of pregnant women
with Lyme disease.

http://www.geocities.com/HotSprings/Oasis/6455/fatalities-biblio.html

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